Results 61 to 70 of about 498,412 (267)

Pilot study of a basic individualized cognitive behavioral therapy program for chronic pain in Japan

BioPsychoSocial Medicine, 2020
Background Chronic pain is a major health problem, and cognitive behavioral therapy (CBT) is its recommended treatment; however, efforts to develop CBT programs for chronic pain and assess their feasibility are remarkably delayed in Asia.
Hiroki Hosogoshi, Kazunori Iwasa, Takaki Fukumori, Yuriko Takagishi, Yoshitake Takebayashi, Tomonori Adachi, Yuki Oe, Yukino Tairako, Yumiko Takao, Hiroyuki Nishie, Ayako Kanie, Masaki Kitahara, Kiyoka Enomoto, Hirono Ishii, Issei Shinmei, Masaru Horikoshi, Masahiko Shibata   +16 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Estructura Factorial Preliminar de la Escala de Creencias de Mujeres de O´Kelly en Población Mexicana

Avances en Psicología Latinoamericana, 2011
La versión mexicana de la australiana o’Kelly Women’s Belief scales fue administrada a una muestra de 363 mujeres nacidas y residentes en México. el análisis factorial con rotación varimax y con autovalor de 3 mostró 36 reactivos de los 92 originales en ...
Arturo Heman Contreras, Leonor Lega, Margarita Villaseñor Ponce, Ana Paulina Alva Jimenez, Lorena Garcia Guerrero   +4 more
doaj  

Applicability and adaptation of cognitive behavior therapy for long COVID neuropsychiatric symptoms: a review with insights from ME/CFS

BMC Infectious Diseases
Background Long COVID presents a spectrum of persistent symptoms that substantially overlap with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), including debilitating fatigue, post-exertional malaise, cognitive dysfunction, and ...
Naoki Takamatsu, Hironori Kuga
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A Brief History of Aaron T. Beck, MD, and Cognitive Behavior Therapy

Clinical Psychology in Europe, 2021
Judith S. Beck, Sarah Fleming
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Psychological treatments for mental health symptoms associated with COVID‐19 infection: A scoping review

PCN Reports
The aim of this scoping review was to synthesize published studies and ongoing clinical trials of psychological interventions for mental health problems associated with COVID‐19 infection.
So Sugita, Kotone Hata, Krandhasi Kodaiarasu, Naoki Takamatsu, Kentaro Kimura, Christian Miller, Lecsy Gonzalez, Ikue Umemoto, Keitaro Murayama, Tomohiro Nakao, Shinsuke Kito, Masaya Ito, Hironori Kuga   +12 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source