Results 41 to 50 of about 1,843,143 (356)
Model selection and prediction of outcomes in recent onset schizophrenia patients who undergo cognitive training. [PDF]
, 2018 Predicting treatment outcomes in psychiatric populations remains a challenge, but is increasingly important in the pursuit of personalized medicine. Patients with schizophrenia have deficits in cognition, and targeted cognitive training (TCT) of auditory
Carter, Cameron S +7 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Stressors affect human motor timing during spaceflight
npj MicrogravityCrewed outer-space missions require adequate motor capacity among astronauts, whose sensorimotor system is disturbed by microgravity. Stressors other than microgravity, e.g., sleep loss, confinement, and high workload, characterize the living experience ...
Yu Tian +7 more
doaj +1 more source
Frontiers in Human Neuroscience, 2016 Detailed knowledge about online brain processing during the execution of complex motor tasks with a high motion range still remains elusive. The aim of the present study was to investigate the hemodynamic responses within sensorimotor networks as well as
Daniel eCarius +8 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Intradialytic Cognitive and Exercise Training May Preserve Cognitive Function
Kidney International Reports, 2018 Cognitive decline is common and increases mortality risk in hemodialysis patients. Intradialytic interventions like cognitive training (CT) and exercise training (ET) may preserve cognitive function.
Mara A. McAdams-DeMarco +8 more
doaj +1 more source
Moderators, mediators and nonspecific predictors of outcome after cognitive rehabilitation of executive functions in a randomised controlled trial [PDF]
, 2017 Moderators, mediators and nonspecific predictors of treatment after cognitive rehabilitation of executive functions in a randomised controlled trial Objective: To explore moderators, mediators and nonspecific predictors of executive functioning after ...
Evans, Jonathan +5 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Frontiers in Aging, 2022 Background: Dementia is the one of the most common and prominent disease in the elderly person that results in the Cognitive interventions. In this study, we aim to conceptualize the cognitive intervention for older adults with and without cognitive ...
Liliana Mendes +3 more
doaj +1 more source
Transcranial electric stimulation and cognitive training improves face perception [PDF]
, 2014 Recently, there has been much interest the effectiveness of cognitive training programmes across a variety of cognitive and perceptual domains. Some evidence suggests that combining training programmes with noninvasive brain stimulation techniques such ...
Banissy, M.J. +4 more
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