Results 61 to 70 of about 268,317 (268)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

[Pd(dach)Cl₂] Complex Targets Proteins Involved in Ribosomal Biogenesis, and RNA Splicing in HeLa Cells

Inorganics
This study aims to investigate the effect of the Pd(II) complex on HeLa cells using computational biology and proteomic analysis. [Pd(dach)Cl2]-treated HeLa cells were subjected to comparative proteomics analysis using label-free data-independent liquid ...
Vanja Ralić, Katarina Davalieva, Branislava Gemović, Milan Senćanski, Maja D. Nešić, Jelena Žakula, Milutin Stepić, Marijana Petković   +7 more
doaj   +1 more source

Measurement of the Wigner distribution function of non-separable laser beams employing a toroidal mirror

New Journal of Physics, 2014
We present a new experimental approach to determine the Wigner distribution function of non-separable laser beams. A rotatable toroidal mirror is employed to focus an IR laser beam at a wavelength of $1064\;{\rm nm}$ .
Tobias Mey, Bernd Schäfer, Klaus Mann
doaj   +1 more source

A Note on the Equivalence of Coherence and Constrained Coherence

Minds and Machines, 2015
Constrained coherence is compared to coherence and its role in the behavioural interpretation of coherence is discussed. The equivalence of these two notions is proven for coherent conditional previsions, showing that the same course of reasoning applies to several similar concepts developed in the realm of imprecise probability theory.
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Incoherent Shock and Collapse Singularities in Non-Instantaneous Nonlinear Media

Applied Sciences, 2018
We study the dynamics of a partially incoherent optical pulse that propagates in a slowly responding nonlinear Kerr medium. We show that irrespective of the sign of the dispersion (either normal or anomalous), the incoherent pulse as a whole exhibits a ...
Gang Xu, Adrien Fusaro, Josselin Garnier, Antonio Picozzi   +3 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Chronic stress disrupts neural coherence between cortico-limbic structures

Frontiers in Neural Circuits, 2013
Chronic stress impairs cognitive function, namely on tasks that rely on the integrity of cortico-limbic networks. To unravel the functional impact of progressive stress in cortico-limbic networks we measured neural activity and spectral coherences ...
João Filipe Oliveira, João Filipe Oliveira, Nuno Sérgio Dias, Nuno Sérgio Dias, Nuno Sérgio Dias, Mariana eCorreia, Mariana eCorreia, Filipa eGama-Pereira, Filipa eGama-Pereira, Vanessa Morais Sardinha, Vanessa Morais Sardinha, Ana eLima, Ana eLima, Ana Filipa Oliveira, Ana Filipa Oliveira, Luís Ricardo Jacinto, Luís Ricardo Jacinto, Luís Ricardo Jacinto, Daniela Silva Ferreira, Daniela Silva Ferreira, Ana Maria Silva, Ana Maria Silva, Joana Santos Reis, Joana Santos Reis, João José Cerqueira, João José Cerqueira, Nuno eSousa, Nuno eSousa   +27 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source