Results 41 to 50 of about 8,132 (273)

Generalized pencils of rays in statistical wave optics [PDF]

open access: yes, 1983
The recently introduced generalized pencil of Sudarshan which gives an exact ray picture of wave optics is analysed in some situations of interest to wave optics.
Simon, R
core   +2 more sources

Statistical moments-based OSNR monitoring for coherent optical systems

open access: yesOptics Express, 2012
We present a novel statistical moments-based method for optical signal-to-noise ratio (OSNR) monitoring in polarization-multiplexed (pol-mux) coherent optical systems. This technique only requires the knowledge of the envelope of the equalized signal before phase correction, which can be achieved by using any two arbitrary statistical moments, and it ...
Chen, Zhu   +7 more
openaire   +2 more sources

Statistical Properties of Phase-Decorrelation in Phase-Resolved Doppler Optical Coherence Tomography [PDF]

open access: yesIEEE Transactions on Medical Imaging, 2009
Decorrelation noise limits the ability of phase-resolved Doppler optical coherence tomography systems to detect smaller vessels exhibiting slower flow velocities, which limits the utility of the technique in many clinical and biological settings. An understanding of the statistical properties of decorrelation noise can aid in the optimal design of ...
Benjamin J. Vakoc   +2 more
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Retrodictive states and two-photon quantum imaging [PDF]

open access: yes, 2003
We use retrodictive quantum theory to analyse two-photon quantum imaging systems.
Pegg, D.T.   +3 more
core   +3 more sources

Innovative Multi-Site Photoplethysmography Analysis for Quantifying Pulse Amplitude and Timing Variability Characteristics in Peripheral Arterial Disease

open access: yesDiseases, 2018
Photoplethysmography (PPG) is a simple-to-perform vascular optics measurement technique that can detect blood volume changes in the microvascular bed of tissue.
Michael Bentham   +2 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Coherence engineering of partially coherent vortex fields: theory, metrology, and applications

open access: yesAdvances in Physics: X
Partially coherent vortex fields combine optical singularities with controllable statistical correlations, forming an important research platform at the intersection of singular optics, statistical optics, and structured-light science.
Jun Zeng   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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