Results 61 to 70 of about 55,652 (271)

Statistical evaluation of reader variability in assessing the diagnostic performance of optical coherence tomography [PDF]

Journal of Biomedical Optics, 2020
Optical coherence tomography (OCT) is widely used as a potential diagnostic tool for a variety of diseases including various types of cancer. However, sensitivity and specificity analyses of OCT in different cancers yield results varying from 11% to 100%.
Erickson-Bhatt, Sarah J., Simpson, Douglas G., Boppart, Stephen A.   +2 more
openaire   +2 more sources

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Influence of laser spot size at diffuser plane on the longitudinal spatial coherence function of optical coherence microscopy system

, 2019
Coherence properties and wavelength of light sources are indispensable for optical coherence microscopy/tomography as they greatly influence the signal to noise ratio, axial resolution, and penetration depth of the system.
Ahmad, Azeem, Butola, Ankit, Dubey, Vishesh, Joshi, Rakesh, Mehta, Dalip Singh, Usmani, Kashif   +5 more
core   +1 more source

Statistics of laser frequency fluctuations in coherent optical receivers

Electronics Letters, 1986
We present a simple model for the statistics of the measured IF frequency in coherent optical receivers, for the case of major interest where the IF bandwidth is large compared with the linewidths of the signal and local oscillator lasers. We show that the PDF for the measured IF frequency is close to Gaussian in this case, with variance depending on ...
I. Garrett, G. Jacobsen
openaire   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

The Properties of Outer Retinal Band Three Investigated With Adaptive-Optics Optical Coherence Tomography. [PDF]

, 2017
PurposeOptical coherence tomography's (OCT) third outer retinal band has been attributed to the zone of interdigitation between RPE cells and cone outer segments. The purpose of this paper is to investigate the structure of this band with adaptive optics
Azimipour, Mehdi, Gorczynska, Iwona, Jonnal, Ravi S, Migacz, Justin V, Werner, John S, Zawadzki, Robert J   +5 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

QuantEYE: The Quantum Optics Instrument for OWL

, 2005
QuantEYE is designed to be the highest time-resolution instrument on ESO:s planned Overwhelmingly Large Telescope, devised to explore astrophysical variability on microsecond and nanosecond scales, down to the quantum-optical limit.
Barbieri, C., Dravins, D., Fosbury, R. A. E., Naletto, G., Nilsson, R., Occhipinti, T., Tamburini, F., Uthas, H., Zampieri, L.   +8 more
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Experimental violation of a Bell-like inequality with optical vortex beams [PDF]

, 2015
Optical beams with topological singularities have a Schmidt decomposition. Hence, they display features typically associated with bipartite quantum systems; in particular, these classical beams can exhibit entanglement. This classical entanglement can be
Agarwal, G. S., Hradil, Z., Motka, L., Rehacek, J., Sanchez-Soto, L. L., Stoklasa, B.   +5 more
core   +3 more sources