Results 51 to 60 of about 16,988 (191)

Holographic coherent anti-Stokes Raman scattering bio-imaging

Biomedical Optics Express, 2012
CARS holography captures both the amplitude and the phase of a complex anti-Stokes field, and can perform three-dimensional imaging by digitally focusing onto different depths inside a specimen. The application of CARS holography for bio-imaging is demonstrated. It is shown that holographic CARS imaging of sub-cellular components in live HeLa cells can
Shi, Kebin, Edwards, Perry S., Hu, Jing, Xu, Qian, Wang, Yanming, Psaltis, Demetri, Liu, Zhiwen   +6 more
openaire   +2 more sources

Single‐Cell Metabolic Imaging and Digital Scoring of Fat Tissue Remodeling by Label‐Free Metabolic Microscopy

Advanced Science, EarlyView.
Mid‐infrared optoacoustic microscopy (MiROM) acquires lipid‐ and protein‐ associated vibrational contrast in intact fat tissue without dyes, preserving native tissue architecture. Through lateral and axial segmentation, MiROM tracks intrinsic intracellular changes during postnatal remodeling. A quantitative spatial analysis tool (Q‐SAT) maps white‐ and
Myeongseop Kim, Constantin Berger, Alexander Wolf, Alina Peteranderl, Martin Klingenspor, Vasilis Ntziachristos, Yongguo Li, Miguel A. Pleitez   +7 more
wiley   +1 more source

Thousand foci coherent anti-Stokes Raman scattering microscopy

APL Photonics
We demonstrate coherent anti-Stokes Raman scattering (CARS) microscopy with 1089 foci, enabled by a high repetition rate amplified oscillator and an optical parametric amplifier.
Dominykas Gudavičius, Lukas Kontenis, Wolfgang Langbein   +2 more
doaj   +1 more source

Phase aspects of (broadband) stimulated Raman scattering

Reviews in Analytical Chemistry, 2012
The phase of the molecular response can be exploited to improve selectivity without sacrificing speed in both narrowband and broadband coherent anti-Stokes Raman scattering (CARS) microscopy, both of which will be considered in this review of the work ...
Offerhaus Herman L., Garbacik Erik T., van Rhijn Alexander C.W., Fussell Andrew L., Herek Jennifer L.   +4 more
doaj   +1 more source

Insights into solid dosage forms with nonlinear optical imaging

Journal of Medical Science, 2023
Microscopic chemical and solid-state structures and their changes in solid drugs and dosage forms can profoundly affect pharmaceutical performance and patient safety.
Teemu Tomberg, Alba Maria Arbiol Enguita , Clare Strachan   +2 more
doaj   +1 more source

High‐Content SRS Imaging Unveils Altered Cholesterol Metabolism in Ovarian Cancers Under CAR‐T Treatment

Advanced Science, EarlyView.
High‐content Stimulated Raman Scattering (SRS) Imaging reveals that ovarian cancer cells surviving Chimeric Antigen Receptor (CAR) ‐T cell challenge exhibit increased cholesterol esterification. Pharmacological inhibition of this pathway with Avasimibe significantly enhances CAR‐T induced killing of ovarian cancer cells by reducing cancer cell ...
Chinmayee V. Prabhu Dessai, Zhuoying Huang, Haonan Lin, Guangrui Ding, Hongjian He, Menna Siddiqui, Meng Zhang, Wilson Wong, Ji‐Xin Cheng   +8 more
wiley   +1 more source

Coherent Anti-Stokes Hyper-Raman Spectroscopy

Nature Communications
Coherent Raman scattering spectroscopies have been established as a powerful tool for investigating molecular systems with high chemical specificity. The existing coherent Raman scattering techniques detect only Raman active modes, which are a part of ...
Kazuki Inoue, Masanari Okuno
doaj   +1 more source

Non-linear label-free imaging through a multimode graded index optical fibre [PDF]

EPJ Web of Conferences, 2020
In recent years, great advances have been made in developing minimal footprint micro-endoscopes using multimode optical fibres (MMF) [1]. By employing wavefront shaping methods the seemingly random speckle pattern resulting from the guiding of coherent ...
Cifuentes Angel, Trägårdh Johanna, Pikálek Tomáš, Šerý Mojmír, Akimov Denis, Meyer Tobias, Popp Jürgen, Amezcua-Correa Rodrigo, Čižmár Tomáš   +8 more
doaj   +1 more source

Resonance enhanced coherent anti-Stokes Raman scattering. [PDF]

Proceedings of the National Academy of Sciences, 1976
Resonance enhancement of coherent anti-Stokes Raman scattering due to the proximity of the laser frequencies to an electronic transition has been demonstrated for dilute solutions of diphenyloctatetrane in benzene. The Raman contribution to the third order susceptibility is shown to be complex near an electronic resonance and the resulting features of ...
B, Hudson, W, Hetherington, S, Cramer, I, Chabay, G K, Klauminzer   +4 more
openaire   +2 more sources

Application of Neural Networks for Advanced Ir Spectroscopy Characterization of Ceria Catalysts Surfaces

Advanced Intelligent Discovery, EarlyView.
A novel convolutional neural network architecture enables rapid, unsupervised analysis of IR spectroscopic data from DRIFTS and IRRAS. By combining synthetic data generation with parallel convolutional layers and advanced regularization, the model accurately resolves spectral features of adsorbed CO, offering real‐time insights into ceria surface ...
Mehrdad Jalali, Lachlan Caulfield, Eric Sauter, Alexei Nefedov, Chengwu Yang, Christof Wöll   +5 more
wiley   +1 more source