Results 51 to 60 of about 297,164 (259)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Pixel-Reassigned Spectral-Domain Optical Coherence Tomography

open access: yesIEEE Photonics Journal, 2018
A novel method of pixel reassignment (PRA) is proposed to achieve transverse superresolution in the confocal microscopy. Inspired by it, for the first time, we report a pixel-reassigned spectral-domain optical coherence tomography (OCT) with $\sim$1.5 ...
En Bo   +4 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Coherent Raman spectro-imaging with laser frequency combs

open access: yes, 2013
Optical spectroscopy and imaging of microscopic samples have opened up a wide range of applications throughout the physical, chemical, and biological sciences.
Bernhardt, Birgitta   +5 more
core   +1 more source

Coherent Multi-Transducer Ultrasound Imaging [PDF]

open access: yesIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2019
An extended aperture has the potential to greatly improve ultrasound imaging performance. This work extends the effective aperture size by coherently compounding the received radio frequency data from multiple transducers. A framework is developed in which an ultrasound imaging system consisting of $N$ synchronized matrix arrays, each with partly ...
Laura Peralta   +5 more
openaire   +5 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Coherent XUV Multispectral Diffraction Imaging in the Microscale

open access: yesApplied Sciences, 2022
The rapid growth of nanotechnology has increased the need for fast nanoscale imaging. X-ray free electron laser (XFEL) facilities currently provide such coherent sources of directional and high-brilliance X-ray radiation.
Stylianos Petrakis   +15 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Computational Theory and Experimental Research on Coherent Optical Imaging

open access: yesApplied Sciences
Since the advent of lasers, coherent optical imaging has found significant applications in optical precision measurement. Among these, digital holography is a key research area.
Junchang Li   +4 more
doaj   +1 more source

Shear Wave Elastography Based on Noise Correlation and Time Reversal

open access: yesFrontiers in Physics, 2021
Shear wave elastography (SWE) relies on the generation and tracking of coherent shear waves to image the tissue's shear elasticity. Recent technological developments have allowed SWE to be implemented in commercial ultrasound and magnetic resonance ...
Javier Brum   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy