Results 1 to 10 of about 11,558 (295)

Coherent Stokes Raman scattering microscopy (CSRS)

open access: yesNature Communications, 2023
We report the first implementation of laser scanning coherent Stokes Raman scattering (CSRS) microscopy. To overcome the major challenge in CSRS imaging, we show how to suppress the fluorescence background by narrow bandpass filter and a lock-in based ...
Sandro Heuke, Hervé Rigneault
doaj   +7 more sources

Broadband Coherent Raman Scattering Microscopy [PDF]

open access: yesLaser and Photonics Reviews, 2018
AbstractSpontaneous Raman (SR) microscopy allows label‐free chemically specific imaging based on the vibrational response of molecules; however, due to the low Raman scattering cross section, it is intrinsically slow. Coherent Raman scattering (CRS) techniques, by coherently exciting vibrational oscillators in the focal volume, increase signal levels ...
Dario Polli   +2 more
exaly   +5 more sources

Uses of coherent Raman scattering microscopy in neuroscience [PDF]

open access: yesFrontiers in Neuroscience
Multiphoton microscopy allows the imaging of biological phenomena deep within brain tissues and has greatly advanced knowledge in neuroscience. However, many optical phenomena other than the multiphoton excitation of fluorophores in nonlinear optics are ...
Mutsuo Nuriya, Mutsuo Nuriya
doaj   +4 more sources

Coherent Raman scattering imaging with a near-infrared achromatic metalens [PDF]

open access: yesAPL Photonics, 2021
Miniature handheld imaging devices and endoscopes based on coherent Raman scattering are promising for label-free in vivo optical diagnosis. Toward the development of these small-scale systems, a challenge arises from the design and fabrication of ...
Peng Lin   +6 more
doaj   +2 more sources

Coherent Raman Scattering Microscopy in Oncology Pharmacokinetic Research [PDF]

open access: yesFrontiers in Pharmacology, 2021
The high attrition rates of anti-cancer drugs during clinical development remains a bottleneck problem in pharmaceutical industry. This is partially due to the lack of quantitative, selective, and rapid readouts of anti-cancer drug activity in situ with ...
Junjie Zeng   +3 more
doaj   +2 more sources

Coherent anti‐Stokes Raman Scattering Microscopy [PDF]

open access: yesChemPhysChem, 2007
AbstractCoherent anti‐Stokes Raman scattering (CARS) microscopy is presented as a new nonlinear optical technique. The combination of vibrational spectroscopy and microscopy allows highly sensitive investigations of unlabelled samples. CARS is an ideal tool for studying a broad variety of samples.
Michiel Müller, Andreas Zumbusch
exaly   +9 more sources

Broadband Coherent Raman Scattering: Excitation Architectures and Operating Regimes [PDF]

open access: yesMolecules
Coherent Raman scattering (CRS) techniques such as coherent anti-Stokes Raman scattering (CARS) provide chemically specific vibrational contrast with signal levels far exceeding spontaneous Raman scattering (SpRS). Extending these to broadband excitation
Roland Ackermann   +4 more
doaj   +2 more sources

Coherent Raman Scattering Microscopy in Biology and Medicine. [PDF]

open access: yesAnnu Rev Biomed Eng, 2015
Advancements in coherent Raman scattering (CRS) microscopy have enabled label-free visualization and analysis of functional, endogenous biomolecules in living systems. When compared with spontaneous Raman microscopy, a key advantage of CRS microscopy is the dramatic improvement in imaging speed, which gives rise to real-time vibrational imaging of live
Zhang C, Zhang D, Cheng JX.
europepmc   +4 more sources

The marriage of coherent Raman scattering imaging and advanced computational tools [PDF]

open access: yesLight: Science & Applications, 2023
Coherent Raman scattering microscopy can provide high-contrast tissue and single-cell images based on the inherent molecular vibrations of the sample. However, conventional techniques face a three-way trade-off between Raman spectral bandwidth, imaging ...
Walker Peterson   +2 more
doaj   +2 more sources

Coherent Raman scattering with plasmonic antennas [PDF]

open access: yesNanophotonics, 2019
Coherent Raman scattering (CRS) techniques are recognized for their ability to induce and detect vibrational coherences in molecular samples. The generation of coherent light fields in CRS produces much stronger signals than what is common in incoherent ...
Fast Alexander, Potma Eric Olaf
doaj   +2 more sources

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