Results 91 to 100 of about 6,267,604 (379)

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Associations between maternal pre-pregnancy BMI and infant striatal mean diffusivity

BMC Medicine
Background It is well-established that parental obesity is a strong risk factor for offspring obesity. Further, a converging body of evidence now suggests that maternal weight profiles may affect the developing offspring’s brain in a manner that confers ...
Aylin Rosberg, Harri Merisaari, John D. Lewis, Niloofar Hashempour, Minna Lukkarinen, Jerod M. Rasmussen, Noora M. Scheinin, Linnea Karlsson, Hasse Karlsson, Jetro J. Tuulari   +9 more
doaj   +1 more source

Long working hours and increased risks of lean non-alcoholic fatty liver disease among Korean men and women

Scientific Reports, 2023
Despite the increasing prevalence of lean nonalcoholic fatty liver disease (NAFLD), its risk factors are not well established. We examined the association between long working hours and incident NAFLD in lean Korean workers with emphasis on sex-based ...
Ga-Young Lim, Yoosoo Chang, Inah Kim, Seungho Ryu, Ria Kwon, Jaechul Song   +5 more
doaj   +1 more source

Cohort Profile: The Canadian Longitudinal Study on Aging (CLSA)

International Journal of Epidemiology, 2019
• A submitted manuscript is the version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to
P. Raina, P. Raina, Christina Wolfson, Christina M. Wolfson, S. Kirkland, Lauren E Griffith, Lauren E Griffith, C. Balion, B. Cossette, I. Dionne, S. Hofer, David B. Hogan, E. R. V. D. Heuvel, T. Liu-Ambrose, V. Menec, Gerald Mugford, Christopher Patterson, H. Payette, B. Richards, H. Shannon, D. Sheets, V. Taler, Mary Thompson, H. Tuokko, A. Wister, Changbao Wu, Lynne Young   +26 more
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Evaluation of Arterial Stiffness and Its Relation to Innovative Anthropometric Indices in Persian Adults

International Journal of Hypertension, 2023
Background. BMI has been evaluated as an old criterion to evaluate obesity in individuals, but it does not assess abdominal obesity and lean mass. We aimed to evaluate the possible relationship of new anthropometric indices (namely, a body shape index ...
Zahra Ataee, Atena Aghaee, Seyyed Reza Sobhani, Elaheh Ebrahimi Miandehi, Parisa Pirzadeh, Maryam Alinezhad-Namaghi, Saeid Eslami, Sahar Sobhani   +7 more
doaj   +1 more source

The Impact of Early Positive Results on a Mathematics and Science Partnership: The Experience of the Institute for Chemistry Literacy Through Computational Science [PDF]

, 2009
After one year of implementation, the Institute for Chemistry Literacy through Computational Science, an NSF Mathematics and Science Partnership Institute Project led by the University of Illinois at Urbana-Champaign’s Department of Chemistry, College of
Henry, M. A., Hogrebe, M. C., Murray, K. S.   +2 more
core   +1 more source

The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort

Annals of Clinical and Translational Neurology, 2018
The Parkinson's Progression Markers Initiative (PPMI) is an observational, international study designed to establish biomarker‐defined cohorts and identify clinical, imaging, genetic, and biospecimen Parkinson's disease (PD) progression markers to ...
K. Marek, S. Chowdhury, A. Siderowf, Shirley Lasch, C. Coffey, C. Caspell-Garcia, T. Simuni, D. Jennings, C. Tanner, J. Trojanowski, L. Shaw, J. Seibyl, N. Schuff, A. Singleton, K. Kieburtz, A. Toga, B. Mollenhauer, D. Galasko, L. Chahine, D. Weintraub, T. Foroud, D. Tosun-Turgut, K. Poston, V. Arnedo, M. Frasier, T. Sherer, S. Bressman, M. Merchant, W. Poewe, C. Kopil, A. Naito, R. Dorsey, C. Casaceli, N. Daegele, J. Albani, L. Uribe, Eric D. Foster, J. Long, N. Seedorff, K. Crawford, Danielle Smith, P. Casalin, G. Malferrari, C. Halter, L. Heathers, D. Russell, S. Factor, P. Hogarth, A. Amara, R. Hauser, J. Jankovic, M. Stern, Shu‐Ching Hu, Gretchen Todd, R. Saunders-Pullman, I. Richard, H. Saint‐Hilaire, K. Seppi, H. Shill, Hubert H. Fernandez, C. Trenkwalder, W. Oertel, D. Berg, Kathrin Brockman, I. Wurster, L. Rosenthal, Yen F. Tai, N. Pavese, P. Barone, S. Isaacson, A. Espay, D. Rowe, M. Brandabur, J. Tetrud, G. Liang, Á. Iranzo, E. Tolosa, K. Marder, Maria de Sanchez, L. Stefanis, M. Marti, J. Martínez, J. Corvol, O. Assly, Salima Brillman, Nir Giladi, Debra Smejdir, Julia Pelaggi, F. Kausar, L. Rees, Barbara Sommerfield, Madeline Cresswell, C. Blair, Karen Williams, Grace A. Zimmerman, S. Guthrie, Ashlee Rawlins, Leigh Donharl, C. Hunter, B. Tran, A. Darin, Heli A. Venkov, Cathi A Thomas, Raymond James, B. Heim, Paul Deritis, F. Sprenger, D. Raymond, D. Willeke, Zoran Obradov, J. Mule, Nancy Monahan, K. Gauss, D. Fontaine, D. Szpak, Arita McCoy, Becky Dunlop, Laura Payne, Susan Ainscough, L. Carvajal, Rebecca Silverstein, Kristy J. Espay, Madelaine B. Rañola, E. Rezola, H. Santana, M. Stamelou, Alicia Garrido, S. Carvalho, G. Kristiansen, Krista Specketer, Anat Mirlman, M. Facheris, H. Soares, A. Mintun, J. Cedarbaum, Peggy Taylor, L. Slieker, Brian McBride, Colin Watson, Etienne Montagut, Z. Sheikh, Baris Bingol, R. Forrat, P. Sardi, T. Fischer, D. Reith, J. Egebjerg, L. Larsen, N. Breysse, D. Meulien, B. Saba, V. Kiyasova, C. Min, Thomas McAvoy, R. Umek, P. Iredale, J. Edgerton, Demetrio Santi, C. Czech, F. Boess, J. Sevigny, T. Kremer, I. Grachev, K. Merchant, A. Avbersek, P. Muglia, Alexandra Stewart, R. Prashad, Johannes Taucher   +168 more
semanticscholar   +1 more source

Cohort migration [PDF]

Demography, 1966
Summary Most migration analyses focus on net migration and are concerned with areal redistributions of population. Migration may also be studied as an event in the life-cycle of an individual, and migration rates may be defined as properties of cohorts. A number of efforts to examine migration as a cohort process has been hampered by the
openaire   +3 more sources

Japanese Legacy Cohorts: Six-Prefecture Cohort Study (Hirayama Cohort Study)

Journal of Epidemiology, 2020
Late Dr Takeshi Hirayama and his colleagues conducted a mortality follow-up of a large-scale cohort in six prefectures in Japan. This study is called the six-prefecture cohort study or Hirayama Cohort Study. The study subjects were residents aged 40 years or older at the baseline survey in 1965, which covered 94.8% of residents identified in the study ...
Suminori Akiba, Suminori Akiba, Yoshihide Kinjo   +2 more
openaire   +5 more sources