Results 91 to 100 of about 3,632,413 (364)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Association of maternal leukocyte, monocyte, and neutrophil counts with hypertensive disorders of pregnancy: the Japan Environment and Children’s Study (JECS)

Scientific Reports
Hypertensive disorders of pregnancy (HDP) increase the risk of preterm births and cesarean delivery. This study aimed to investigate whether maternal blood leukocyte, monocyte, or neutrophil counts in the first trimester are related to the development of
Shiori Ishiyama, Kazuki Mochizuki, Ryoji Shinohara, Kunio Miyake, Megumi Kushima, Reiji Kojima, Sayaka Horiuchi, Sanae Otawa, Hideki Yui, Tadao Ooka, Yuka Akiyama, Hiroshi Yokomichi, Zentaro Yamagata, The Japan Environment and Children’s Study Group   +13 more
doaj   +1 more source

The correlation between early or late natural menopausal age and muscle mass percentage and bone mass percentage in postmenopausal women

Zhongguo gonggong weisheng
ObjectiveTo analyze the correlation between early or late natural menopausal age and muscle mass percentage and bone mass percentage in postmenopausal women, and to provide a reference for health care of postmenopausal women.
Jiaoling LUO, Weisen ZHANG, Zhihao CHAI, Feng ZHU, Tong ZHU, Yali JIN, Jing PAN, Chaoqiang JIANG   +7 more
doaj   +1 more source

Cohort profile: the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS) in Korea

BMJ Open, 2017
Purpose The National Health Insurance Service-Health Screening Cohort (NHIS-HEALS) is a cohort of participants who participated in health screening programmes provided by the NHIS in the Republic of Korea.
S. Seong, Yeon-Yong Kim, Sue-Kyung Park, Y. Khang, H. Kim, Jong Heon Park, Hee-Jin Kang, Cheol-Ho Do, Jong-Sun Song, Eun-Joo Lee, Seongjun Ha, S. Shin, Seung-lyeal Jeong   +12 more
semanticscholar   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Associations between maternal pre-pregnancy BMI and infant striatal mean diffusivity

BMC Medicine
Background It is well-established that parental obesity is a strong risk factor for offspring obesity. Further, a converging body of evidence now suggests that maternal weight profiles may affect the developing offspring’s brain in a manner that confers ...
Aylin Rosberg, Harri Merisaari, John D. Lewis, Niloofar Hashempour, Minna Lukkarinen, Jerod M. Rasmussen, Noora M. Scheinin, Linnea Karlsson, Hasse Karlsson, Jetro J. Tuulari   +9 more
doaj   +1 more source

The Age-Period-Cohort-Interaction Model for Describing and Investigating Inter-Cohort Deviations and Intra-Cohort Life-Course Dynamics [PDF]

arXiv, 2019
Social scientists have frequently sought to understand the distinct effects of age, period, and cohort, but disaggregation of the three dimensions is difficult because cohort = period - age. We argue that this technical difficulty reflects a disconnection between how cohort effect is conceptualized and how it is modeled in the traditional age-period ...
arxiv  

BMI and all cause mortality: systematic review and non-linear dose-response meta-analysis of 230 cohort studies with 3.74 million deaths among 30.3 million participants

British medical journal, 2016
Objective To conduct a systematic review and meta-analysis of cohort studies of body mass index (BMI) and the risk of all cause mortality, and to clarify the shape and the nadir of the dose-response curve, and the influence on the results of confounding ...
D. Aune, A. Sen, M. Prasad, T. Norat, I. Janszky, S. Tonstad, P. Romundstad, L. Vatten   +7 more
semanticscholar   +1 more source

Cohort migration [PDF]

Demography, 1966
Summary Most migration analyses focus on net migration and are concerned with areal redistributions of population. Migration may also be studied as an event in the life-cycle of an individual, and migration rates may be defined as properties of cohorts. A number of efforts to examine migration as a cohort process has been hampered by the
openaire   +3 more sources

Cohort Profile: The Bern Infant Lung Development Cohort [PDF]

International Journal of Epidemiology, 2011
Childhood asthma resembles a complex syndrome rather than a single disease. Clinical manifestations include cough, shortness of breath and wheeze. Because of its high prevalence, it is of major public health relevance. Presentation and disease course of childhood wheezing disorders vary, and its phenotypes are difficult to distinguish in early ...
Fuchs Oliver, Fuchs Oliver, Latzin Philipp, Latzin Philipp, Kuehni Claudia E., Frey Urs, Frey Urs   +6 more
openaire   +5 more sources