Results 111 to 120 of about 3,632,413 (364)

Mortality cohort effect detection and measurement based on differential geometry [PDF]

open access: yesarXiv, 2015
This paper analyzes mortality cohort effect of birth year and develops an approach to identify and measure cohort effects in mortality data set. The approach is based on differential geometry and leads to an explicit result which can describe how strong the cohort effect is in any period.
arxiv  

Cohorting to isolate asymptomatic spreaders: An agent-based simulation study on the Mumbai Suburban Railway [PDF]

open access: yesarXiv, 2020
The Mumbai Suburban Railways, \emph{locals}, are a key transit infrastructure of the city and is crucial for resuming normal economic activity. To reduce disease transmission, policymakers can enforce reduced crowding and mandate wearing of masks. \emph{Cohorting} -- forming groups of travelers that always travel together, is an additional policy to ...
arxiv  

The Probabilistic Explanation of the Cohort Component Population Projection Method [PDF]

open access: yesarXiv, 2021
The probabilistic explanation of the direct and reverse cohort component population projection methods is presented. The main characteristics determining the probability distribution of the values for the direct and reverse component methods are found.
arxiv  

Cohort Profile: The Dutch Perined-Lifelines birth cohort [PDF]

open access: yesPLOS ONE, 2019
Maternal nutrition status (e.g. dietary/nutrient intake) during pregnancy has been associated with pregnancy outcomes including birth weight, infant survival and metabolic health of the offspring during later life. During the past few years, maternal dietary intake, at least three months before conception, has been shown to affect pregnancy outcomes ...
Nastaran Salavati   +3 more
openaire   +5 more sources

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

open access: yesAging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen   +3 more
wiley   +1 more source

Early life vitamin D status and asthma and wheeze: a systematic review and meta-analysis

open access: yesBMC Pulmonary Medicine, 2018
Background Vitamin D deficiency has been linked to an increased risk of asthma. This study aimed to quantify the effect of early life vitamin D status on asthma and wheeze later in life.
Song-Ying Shen   +8 more
doaj   +1 more source

Thoughts on new statistical procedures for age-period-cohort analyses [PDF]

open access: yesarXiv, 2009
Age-period-cohort analysis is mathematically intractable because of fundamental nonidentifiability of linear trends. However, some understanding can be gained in the context of individual problems.
arxiv  

Idarucizumab for Dabigatran Reversal — Full Cohort Analysis

open access: yesNew England Journal of Medicine, 2017
Background Idarucizumab, a monoclonal antibody fragment, was developed to reverse the anticoagulant effect of dabigatran. Methods We performed a multicenter, prospective, open‐label study to determine whether 5 g of intravenous idarucizumab would be able
C. Pollack   +20 more
semanticscholar   +1 more source

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

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