Results 191 to 200 of about 4,817,088 (306)

Cohort Profile: The Swedish National March Cohort [PDF]

International Journal of Epidemiology, 2016
Trolle Lagerros, Y, HANTIKAINEN, ESSI MARJATTA, Mariosa, D, Ye, W, Adami, H, Grotta, A, Ghilotti, F, BELLOCCO, RINO   +7 more
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A U-Shaped Association Between Blood mtDNA Copy Number and Risk of Type 2 Diabetes. [PDF]

Diabetes Care
Huang X, Tian Z, Pan Y, Zhang J, Wu B, Gao S, Cheng Y, Hu Q, Ma J, Pan Q, Shao J, Zhou K.   +11 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Cohort Profile: The Urmia Lake Cohort Study (ULCS)

International Journal of Epidemiology, 2022
Javad Aghazadeh-Attari, Hossein Poustchi, Davoud Vahabzadeh, Ramin Shakeri, Rasool Entezar Mahdi, Habibollah Pirnejad, Sareh Eghtesad, Zahra Mohammadi, Maryam Sharafkhah, Amaneh Shayanrad, Neda Valizadeh, Mohammadreza Pashaei, Nilsa Dourandish, Maryam Majidinia, Marjan Kouhnavard, Jamal Ahmadzadeh, Ali Sadaghyanifar, Iraj Mohebbi   +17 more
openaire   +2 more sources

Cohort profile Davos Alzheimer's Collaborative DAC Egypt Cohort. [PDF]

NPJ Aging
Moustafa SA, Mowafi S, Fawi G, Othman M, Heikal S, Mohamed AS, Habib H, Hassan OA, Meghaed F, Youssef AS, Ali EM, Moustafa R, Mohamed M, Moustafa M, Sweilam J, Wahdan M, Ezzeldin S, Shebl N, Khella K, Tantawi L, Mahmoud F, Gaballah Z, Zaki F, Qansuwa E, El Taras M, Sayed S, El Sayed M, Srour I, El Sayed Moustafa S, Sameer S, Gad ES, Sweilam M, Rizig M, Meier I, Narayan V, Salama M.   +35 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Healthful and unhealthful plant-based diets and site-specific cancer risk: a systematic review and meta-analysis of observational studies. [PDF]

Eur J Nutr
Gil-Lespinard M, Iglesias-Vázquez L, Jakszyn P.   +2 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source