Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
The internal architecture of Declt, our reference manual generator for Common Lisp libraries, is currently evolving towards a three-stages pipeline in which the information gathered for documentation purposes is first reified into a formalized set of object-oriented data structures.
openaire +2 more sources
Cohort profile: the Alma cohort of Swedish children born 2018-2023 - a prospective, register-based resource to study social determinants of health and Swedish child health services. [PDF]
Fäldt A, Durbeej N, Dahlberg A.
europepmc +1 more source
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara +3 more
wiley +1 more source
Cohort fertility patterns and breast cancer mortality among U.S. women, 1948-2003 [PDF]
Epidemiological research has shown that women who have early and numerous births have reduced risks of being diagnosed with breast cancer. We use U.S.
Patrick M. Krueger, Samuel Preston
core
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
A cohort analysis of the income distribution in Chile [PDF]
In this paper we look at the income distribution by cohort in Chile. We construct a synthetic panel from cross section surveys and estimate the income distribution for cohorts born between 1902 and 1978.
Claudio Sapelli
core
Healthcare resource use and costs following RSV-related hospitalizations among US adults aged 50 years and older. [PDF]
Singer D +5 more
europepmc +1 more source
Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen +11 more
wiley +1 more source
Characterization of eccentric hamstring strength and inter-limb asymmetry profiles in national-level youth male soccer players. [PDF]
Wang J +8 more
europepmc +1 more source

