Results 241 to 250 of about 5,101,614 (337)

Effect of Maternity Waiting Home Service Utilization on Perinatal Health Outcomes in Public Hospitals of West Arsi Zone, Oromia Region: Institution Based Prospective Cohort Study

Negeso Gebeyehu Gejo, Abraham Endale Geleta, Maedot Ariaya Haymete, Daniel Yohannes, Aman Urgessa Edaso   +4 more
openalex   +1 more source

Screen time used by adolescents and association with suicide risk: a contribution from a birth cohort in São Luís, Ma

, 2021
Leandro Saldanha Nunes Mouzinho
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Phase II Study of Dabrafenib and Trametinib in Patients With Tumors With <i>BRAF</i>^<i>V600E</i> Mutations: Updated Results From NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol H. [PDF]

JCO Precis Oncol
Salama AKS, Wang V, Macrae ER, Park JI, Chen HX, Gray RJ, McShane LM, Rubinstein LV, Patton D, Williams PM, Hamilton SR, Armstrong DK, Tricoli JV, Conley BA, Arteaga CL, Harris LN, O'Dwyer PJ, Chen AP, Flaherty KT.   +18 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Excluding Ascites From the GEMA-Na Score Does Not Impact Outcome Predictions in Liver Transplant Candidates. [PDF]

Liver Int
Rodríguez-Perálvarez ML, Gómez-Orellana AM, Majumdar A, McCaughan GW, Kalafateli M, Taylor R, de la Rosa G, Aguilera MV, Gastaca M, Cepeda-Franco C, Ortiz ML, Colmenero J, Otero A, González Grande R, Cachero A, Molina Pérez E, Barreales M, Martín Mateos R, Rodríguez-Soler M, Romero M, Dopazo C, Alonso Martín C, Otón E, González Diéguez L, Espinosa MD, Arias Milla A, Blanco Fernández G, Lorente S, Cuadrado Lavín A, Sogbe M, Guijo-Rubio D, Hervás Martínez C, Tsochatzis E.   +32 more
europepmc   +1 more source

Characteristics and Predictors of Multi-system Immune-Related Adverse Events in a Large Pan-Cancer Cohort: A Retrospective Analysis

Contini, Julia, Koh, Min Jung, Trivedi, Charmi, Chu, Jacqueline J., Gupta, Sapana R., Petruzzelli, Curtis, Malani, Kanika, Steuer, Rebecca, Jain, Sandeep, Park, William, Min, May, Hadfield, Matthew   +11 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Strategic sequencing of bladder-sparing therapies in the management of BCG-unresponsive non-muscle invasive bladder cancer. [PDF]

Ann Med
Abou Chakra M, Boormans JL, Hayne D, O'Donnell MA.   +3 more
europepmc   +1 more source

Additional file 1 of Transdiagnostic similarities and distinctions in brain networks associated with autistic social impairments: a prospective cohort study

Bruno, Jennifer L., Plank, Julia R., Leder, Samantha, Lake, Evelyn M.R., Finn, Emily S., Green, Tamar   +5 more
openalex   +1 more source