Results 81 to 90 of about 4,678,570 (340)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Cohort Profile: Mysore Parthenon Birth Cohort [PDF]

International Journal of Epidemiology, 2014
The Mysore Parthenon Birth Cohort was established to examine the long-term effects of maternal glucose tolerance and nutritional status on cardiovascular disease risk factors in the offspring. During 1997-98, 830 of 1233 women recruited from the antenatal clinics of the Holdsworth Memorial Hospital (HMH), Mysore, India, underwent an oral glucose ...
Krishnaveni, G.V., Veena, S.R., Hill, J.C., Karat, S.C., Fall, C.H.   +4 more
openaire   +4 more sources

Association of maternal leukocyte, monocyte, and neutrophil counts with hypertensive disorders of pregnancy: the Japan Environment and Children’s Study (JECS)

Scientific Reports
Hypertensive disorders of pregnancy (HDP) increase the risk of preterm births and cesarean delivery. This study aimed to investigate whether maternal blood leukocyte, monocyte, or neutrophil counts in the first trimester are related to the development of
Shiori Ishiyama, Kazuki Mochizuki, Ryoji Shinohara, Kunio Miyake, Megumi Kushima, Reiji Kojima, Sayaka Horiuchi, Sanae Otawa, Hideki Yui, Tadao Ooka, Yuka Akiyama, Hiroshi Yokomichi, Zentaro Yamagata, The Japan Environment and Children’s Study Group   +13 more
doaj   +1 more source

The correlation between early or late natural menopausal age and muscle mass percentage and bone mass percentage in postmenopausal women

Zhongguo gonggong weisheng
ObjectiveTo analyze the correlation between early or late natural menopausal age and muscle mass percentage and bone mass percentage in postmenopausal women, and to provide a reference for health care of postmenopausal women.
Jiaoling LUO, Weisen ZHANG, Zhihao CHAI, Feng ZHU, Tong ZHU, Yali JIN, Jing PAN, Chaoqiang JIANG   +7 more
doaj   +1 more source

Prevalence of congenital microcephaly and its risk factors in an area at risk of Zika outbreaks

BMC Pregnancy and Childbirth, 2021
Background Prevalence of neonatal microcephaly in populations without Zika-epidemics is sparse. The study aimed to report baseline prevalence of congenital microcephaly and its relationship with prenatal factors in an area at risk of Zika outbreak ...
Songying Shen, Wanqing Xiao, Lifang Zhang, Jinhua Lu, Anna Funk, Jianrong He, Si Tu, Jia Yu, Li Yang, Arnaud Fontanet, Wei Bao, Kar Keung Cheng, Xiu Qiu   +12 more
doaj   +1 more source

Association Between Vestibular Migraine and Migraine Headache: Yet to Explore. [PDF]

, 2020
ObjectivesTo evaluate if patients with a diagnosis of vestibular migraine (VM) by the International Classification of Headache Disorders (ICHD) criteria have meaningful differences in symptomatology and disease characteristics when compared to patients ...
Abouzari, Mehdi, Djalilian, Hamid R, Goshtasbi, Khodayar, Lin, Harrison W, Moshtaghi, Omid, Tan, Donald   +5 more
core  

Drug-related deaths in Scotland 1979-2013: evidence of a vulnerable cohort of young men living in deprived areas [PDF]

, 2018
Background: Even after accounting for deprivation, mortality rates are higher in Scotland relative to the rest of Western Europe. Higher mortality from alcohol- and drug-related deaths (DRDs), violence and suicide (particularly in young adults ...
Bouttell, Janet, Lewsey, James, McCartney, Gerry, Minton, Jon, Parkinson, Jane   +4 more
core   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Japanese Legacy Cohorts: Six-Prefecture Cohort Study (Hirayama Cohort Study)

Journal of Epidemiology, 2020
Late Dr Takeshi Hirayama and his colleagues conducted a mortality follow-up of a large-scale cohort in six prefectures in Japan. This study is called the six-prefecture cohort study or Hirayama Cohort Study. The study subjects were residents aged 40 years or older at the baseline survey in 1965, which covered 94.8% of residents identified in the study ...
Suminori Akiba, Suminori Akiba, Yoshihide Kinjo   +2 more
openaire   +5 more sources