Results 81 to 90 of about 3,632,413 (364)

Prevalence of congenital microcephaly and its risk factors in an area at risk of Zika outbreaks

open access: yesBMC Pregnancy and Childbirth, 2021
Background Prevalence of neonatal microcephaly in populations without Zika-epidemics is sparse. The study aimed to report baseline prevalence of congenital microcephaly and its relationship with prenatal factors in an area at risk of Zika outbreak ...
Songying Shen   +12 more
doaj   +1 more source

The natural history of nonalcoholic fatty liver disease: a population-based cohort study.

open access: yesGastroenterology, 2005
BACKGROUND & AIMS The natural history of nonalcoholic fatty liver disease (NAFLD) in the community remains unknown. We sought to determine survival and liver-related morbidity among community-based NAFLD patients.
L. Adams   +6 more
semanticscholar   +1 more source

Cohort Profile: The 1987 Finnish Birth Cohort [PDF]

open access: yesInternational Journal of Epidemiology, 2011
There is ample evidence showing how marginalization and inequalities in well-being and health have roots in childhood. Preand perinatal factors affect childhood and adolescent outcomes—such as mortality and morbidity, behavioural problems, delinquent and criminal behaviour, cognitive and motor functioning and teenage pregnancies, but the extent to ...
Gissler, Mika, Paananen, Reija
openaire   +4 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Parental divorce in childhood does not independently predict maternal depressive symptoms during pregnancy

open access: yesBMC Pregnancy and Childbirth, 2020
Background This study sought to investigate if parental divorce in childhood increases the risk for depressive symptoms in pregnancy. Methods Women were recruited during their ultrasound screening in gestational week (gwk) 12.
Elviira Porthan   +6 more
doaj   +1 more source

Dietary fiber intake and risk of type 2 diabetes in a general Japanese population: The Hisayama Study

open access: yesJournal of Diabetes Investigation, 2021
Aims/Introduction The investigation of the influence of dietary fiber intake on the incidence of type 2 diabetes in a general Japanese population. Materials and Methods A total of 1,892 individuals aged 40–79 years without diabetes at baseline were ...
Yasumi Kimura   +9 more
doaj   +1 more source

The gut mycobiome of the Human Microbiome Project healthy cohort

open access: yesMicrobiome, 2017
BackgroundMost studies describing the human gut microbiome in healthy and diseased states have emphasized the bacterial component, but the fungal microbiome (i.e., the mycobiome) is beginning to gain recognition as a fundamental part of our microbiome ...
Andrea Nash   +11 more
semanticscholar   +1 more source

Japanese Legacy Cohorts: Six-Prefecture Cohort Study (Hirayama Cohort Study)

open access: yesJournal of Epidemiology, 2020
Late Dr Takeshi Hirayama and his colleagues conducted a mortality follow-up of a large-scale cohort in six prefectures in Japan. This study is called the six-prefecture cohort study or Hirayama Cohort Study. The study subjects were residents aged 40 years or older at the baseline survey in 1965, which covered 94.8% of residents identified in the study ...
Suminori Akiba   +2 more
openaire   +5 more sources

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Cohort Profile Update: The Norwegian Mother and Child Cohort Study (MoBa).

open access: yesInternational Journal of Epidemiology, 2016
This is an update of the Norwegian Mother and Child Cohort Study (MoBa) cohort profile which was published in 2006. Pregnant women attending a routine ultrasound examination were initially invited. The first child was born in October 1999 and the last in
P. Magnus   +14 more
semanticscholar   +1 more source

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