Results 91 to 100 of about 2,269,626 (311)

Magnitude of problematic anger and its predictors in the Millennium Cohort

BMC Public Health, 2020
Background Problematic anger is intense anger associated with elevated generalized distress and that interferes with functioning. It also confers a heightened risk for the development of mental health problems.
Amy B. Adler, Cynthia A. LeardMann, Kimberly A. Roenfeldt, Isabel G. Jacobson, David Forbes, for the Millennium Cohort Study Team   +5 more
doaj   +1 more source

Harmonised Mental Health Measures at Age 10/11 in Selected British Cohorts: National Child Development Study

, 2022
copyright UK Data Service and data collection copyright owner.CLOSER (Cohort and Longitudinal Studies Enhancement Resources) aims to maximise the use, value and impact of longitudinal studies, both at home and abroad.
Cohort and Longitudinal Studies Enhancement Resources
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Association of Japanese cedar pollen sensitization in children with Dermatophagoides pteronyssinus sensitization and maternal sensitization: Insights from the Yamanashi adjunct study within the Japan Environment and Children’s Study (JECS)

Allergology International
Background: In recent years, the prevalence of allergic rhinitis (AR) in Japanese children has increased significantly. Multiple sensitization and genetic factors are associated with the development of AR, and moreover, multiply sensitized children are ...
Ayumi Shimamura, Ryoji Shinohara, Megumi Kushima, Sanae Otawa, Hideki Yui, Tomokazu Matsuoka, Daisuke Watanabe, Hiroshi Yokomichi, Kunio Miyake, Reiji Kojima, Zentaro Yamagata, Daiju Sakurai   +11 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

The growth and development of cohort studies

Annals of Human Biology, 2020
Cohort studies are special forms of longitudinal studies that have long been accepted as the primary designs to acquire information on the interaction between the environment and health and the subsequent aetiology and progression of disease.
Noël Cameron
doaj   +1 more source

Relevance of cohort studies for the study of transplant infectious diseases

, 2012
PURPOSE OF REVIEW: The debate on the merits of observational studies as compared with randomized trials is ongoing. We will briefly touch on this subject, and demonstrate the role of cohort studies for the description of infectious disease patterns after
Khanna, N., Cusini, A., Meylan, P., Manuel, Oriol, Garzoni, C., Manuel, O., Mueller, N.J., Hirsch, H.H., Hirsch, Hans H, Berger, C., Koller, Michael, Meylan, Pascal, Boggian, Katia, Cusini, Alexia, Nadal, D., Mueller, N. J., Mueller, Nicolas J, Koller, M., Berger, Christoph, Boggian, K., Weisser, Maja, van Delden, C., van Delden, Christian, Weisser, M., Hirsch, H. H., Khanna, Nina, Garzoni, Christian, Nadal, David   +27 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The use of new technologies in Cohort studies [PDF]

Revista Brasileira em Promoção da Saúde, 2010
Existem relatos de trabalhos observacionais, longitudinais, desde século XVIII. Um dos primeiros trabalhos nesta linha consistiu no acompanhamento de filhos de pacientes tuberculosos por cerca de 20 anos(1).
Carlos Antonio Bruno da Silva, Querubina Bringel Olinda   +1 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source