Results 81 to 90 of about 2,269,626 (311)

Adult consequences of late adolescent alcohol consumption: a systematic review of cohort studies. [PDF]

, 2011
BACKGROUND: Although important to public policy, there have been no rigorous evidence syntheses of the long-term consequences of late adolescent drinking.
McAlaney, J., McAlaney J., Rowe, Richard, McAlaney John, Rowe Richard, John McAlaney, McCambridge Jim, Rowe, R., McCambridge J., McCambridge, Jim, McAlaney, John, Jim McCambridge, Richard Rowe, McCambridge, J.   +13 more
core   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

The Millennium Cohort Study.

Population trends, 2002
The Millennium Cohort Study is the latest in the line of British birth cohort studies. MCS resembles its predecessors which follow people born in 1946, 1958 and 1970 in the intention to become multi-purpose longitudinal data resource charting many aspects of individual's lives over time.
Smith, K, Joshi, H
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A cohort profile of the Graham Roberts study cohort

Frontiers in Oncology
PurposeThe Graham Roberts Study was initiated in 2018 and is the first Trials Within Cohorts (TwiCs) study for bladder cancer. Its purpose is to provide an infrastructure for answering a breadth of research questions, including clinical, mechanistic, and supportive care centred questions for bladder cancer patients.ParticipantsAll consented patients ...
Russell, Beth, Leech, Poppy, Wylie, Harriet, Moss, Charlotte, Haire, Anna, Enting, Deborah, Amery, Suzanne, Chatterton, Kathryn, Khan, Muhammad Shamin, Thurairaja, Ramesh, Nair, Rajesh, Malde, Sachin, Smith, Kate, Gillett, Cheryl, Josephs, Debra, Pintus, Elias, Rudman, Sarah, Hughes, Simon, Relton, Clare, Van Hemelrijck, Mieke   +19 more
openaire   +4 more sources

COVID-19 Survey in Five National Longitudinal Cohort Studies: Millennium Cohort Study, Next Steps, 1970 British Cohort Study and 1958 National Child Development Study, 2020-2021

, 2020
copyright UK Data Service and data collection copyright owner.The Centre for Longitudinal Studies (CLS) and the MRC Unit for Lifelong Health and Ageing (LHA) have carried out two online surveys of the participants of five national longitudinal cohort ...
University College London, UCL Institute of Education, Centre for Longitudinal Studies
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Sex Differences in Birth Weight and Physical Activity in Japanese Schoolchildren

Journal of Epidemiology, 2018
Background: Lower birth weight (BW) is associated with increased chronic disease risk later in life. Previous studies suggest that this may be mediated principally via physical activity (PA). However, the association between BW and PA in children has not
Mitsuya Yamakita, Miri Sato, Kohta Suzuki, Daisuke Ando, Zentaro Yamagata   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Sex-specific association between carbohydrate antigen 19–9 and incident type 2 diabetes

Scientific Reports
Carbohydrate antigen 19–9 (CA19-9) levels are associated with glycemic control, insulin resistance, and chronic complications in patients with type 2 diabetes (T2D). Women generally show higher CA19-9 levels despite a greater T2D prevalence in men.
Sujeong Shin, Yoosoo Chang, Seungho Ryu
doaj   +1 more source