Results 111 to 120 of about 3,959,577 (361)
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022 One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen +3 more
wiley +1 more source
The growth and development of cohort studies
Annals of Human Biology, 2020 Cohort studies are special forms of longitudinal studies that have long been accepted as the primary designs to acquire information on the interaction between the environment and health and the subsequent aetiology and progression of disease.
Noël Cameron
doaj +1 more source
Cohort Profile: Melbourne Atopy Cohort study (MACS) [PDF]
International Journal of Epidemiology, 2016 Advance Access Publication Date: 21 April 2016 ; Adrian J Lowe, Caroline J Lodge, Katrina J Allen, Michael J Abramson, Melanie C Matheson, Paul S Thomas, Christopher A Barton, Catherine M Bennett, Bircan Erbas, Cecilie Svanes, Mathias Wjst, Francisco G, omez Real, Jennifer L Perret, Melissa A Russell, Melissa C Southey, John L Hopper, Lyle C Gurrin ...
Cecilie Svanes +24 more
openaire +4 more sources
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Aggressive Behavior, Volume 49, Issue 1, Page 5-14, January 2023., 2023 Abstract This study uses longitudinal data from the UK Millennium Cohort Study (N = 13,277) to examine the childhood and early adolescence factors that predict weapon involvement in middle adolescence, which in this study is exemplified by having carried or used a weapon.
Aase Villadsen, Emla Fitzsimons
wiley +1 more source
Treatment for congenital toxoplasmosis: finding out what works [PDF]
, 2009 Evidence for the effectiveness of prenatal or postnatal treatment for congenital toxoplasmosis will be critical to guide policy about prenatal and neonatal screening over the next 10 years, let alone the next 100.
Gilbert, R
core +3 more sources
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
Factors modulating 99mTc‐MAA planar lung dosimetry for 90Y radioembolization
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Purpose To investigate the accuracy and biases of predicted lung shunt fraction (LSF) and lung dose (LD) calculations via 99mTc‐macro‐aggregated albumin (99mTc‐MAA) planar imaging for treatment planning of 90Y‐microsphere radioembolization.
Benjamin P. Lopez +4 more
wiley +1 more source
Education, First Occupation and Later Occupational Attainment: Cross-cohort Changes among Men and Women in Britain [PDF]
, 2009 This paper examines cohort and gender differences in occupational attainment in Britain. Using data from the three British Birth Cohort studies, I investigate the process of occupational attainment up to age 34 using a scale based on occupational ...
Bukodi, Erzsebet
core +1 more source