Results 191 to 200 of about 15,938,609 (293)

Frailty, trajectories of frailty, and cognitive impairment: evidence from five longitudinal cohort studies. [PDF]

BMC Public Health
Peng L, Chen Z, Li L, Zhang S.
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

The Complex Dynamics of Healthism in Birth Cohort Studies: Comparative Perspectives From the United Kingdom, the Netherlands, Brazil and Portugal. [PDF]

Sociol Health Illn
Gibbon S, Tize C, Riley T, Muniz T.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Human metapneumovirus infection in pregnancy: A systematic review of cohort studies and case reports. [PDF]

World J Virol
Tsantila A, Gourounti K, Nanou C, Metallinou D, Georgakopoulou VE, Bolou A, Diamanti A.   +6 more
europepmc   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Thymic Involution and Function in People With HIV and General Population Controls: A Cross-Sectional Analysis From Two Danish Cohort Studies. [PDF]

Aging Cell
Vanbellinghen MC, Boyd A, Johansen AO, Suarez-Zdunek MA, Knudsen AD, Kristensen TS, Kühl JT, Sigvardsen PE, Pham MHC, Larsen AF, Kofoed KF, Nordestgaard BG, Afzal S, Kootstra N, Nielsen SD, Reiss P.   +15 more
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Birthweight and cardiometabolic risk factors in offspring: A systematic review and meta-analysis of cohort studies. [PDF]

Arch Public Health
Zhu C, Ding Y, Chen L, Zhai S, Li Y.
europepmc   +1 more source

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source