Insulin resistance and the risk of dementia: a systematic review and meta-analysis of prospective cohort studies. [PDF]
Xu X, Li J, Pan H, Zhao B, Wang D.
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Sleep disturbances and risk of Alzheimer's disease: a systematic review and meta-analysis of longitudinal cohort studies. [PDF]
Li Q +11 more
europepmc +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Long-term glycemic variability and risk of peripheral artery disease: a systematic review and meta-analysis of cohort studies. [PDF]
Xia J, Peng Q, Chen L, Liu C, Zhu T.
europepmc +1 more source
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec +6 more
wiley +1 more source
Habitual physical activity and sarcopenia: a systematic review and meta-analysis of prospective cohort studies. [PDF]
Dai D +6 more
europepmc +1 more source
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source
Outcome switching in cohort studies of interventions: meta-epidemiological study.
Song Z +6 more
europepmc +1 more source
"Foot and Ankle Risk Factors for Future Falls in Older Adults: A Systematic Review With Meta-Analysis of Prospective Cohort Studies". [PDF]
Valeriani S, Melotto G, Tunprasert T.
europepmc +1 more source

