Results 81 to 90 of about 3,959,577 (361)

Long-term weight loss effects on all cause mortality in overweight/obese populations [PDF]

, 2007
This systematic review assesses the long-term effectiveness of weight loss on all cause mortality in overweight/obese people. Medline, Embase and Cinahl were searched (1966–2005). Cohort studies and trials on participants with Body Mass Index ¡Ý25 kg/m2,
Aucott, Lorna S, Avenell, Alison, Boom, John, Jung, Roland, Poobalan, Amudha S, Smith, W Cairns S   +5 more
core   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Long‐Term Particulate Matter Exposure and Incidence of Arrhythmias: A Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Studies have shown that short‐term exposure to air pollution is associated with cardiac arrhythmia hospitalization and mortality. However, the relationship between long‐term particulate matter air pollution and arrhythmias is still unclear. We
Zhenyu Zhang, Jeonggyu Kang, Yun Soo Hong, Yoosoo Chang, Seungho Ryu, Jihwan Park, Juhee Cho, Eliseo Guallar, Ho Cheol Shin, Di Zhao   +9 more
doaj   +1 more source

Artificial intelligence for diagnosing and predicting survival of patients with renal cell carcinoma: Retrospective multi-center study [PDF]

arXiv, 2023
Background: Clear cell renal cell carcinoma (ccRCC) is the most common renal-related tumor with high heterogeneity. There is still an urgent need for novel diagnostic and prognostic biomarkers for ccRCC. Methods: We proposed a weakly-supervised deep learning strategy using conventional histology of 1752 whole slide images from multiple centers.
arxiv  

Sexually transmitted infection as a risk factor for homosexual HIV transmission: a systematic review of epidemiological studies

, 2000
Existing reviews suggest some sexually transmitted infections (STIs) are risk factors in heterosexual HIV transmission. This may not be so in homosexual HIV transmission, about which reviews make no specific conclusions.
Bonell, C, Hickson, F, Weatherburn, P
core   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Early life vitamin D status and asthma and wheeze: a systematic review and meta-analysis

BMC Pulmonary Medicine, 2018
Background Vitamin D deficiency has been linked to an increased risk of asthma. This study aimed to quantify the effect of early life vitamin D status on asthma and wheeze later in life.
Song-Ying Shen, Wan-Qing Xiao, Jin-Hua Lu, Ming-Yang Yuan, Jian-Rong He, Hui-Min Xia, Xiu Qiu, Kar Keung Cheng, Kin Bong Hubert Lam   +8 more
doaj   +1 more source

A descriptive analysis of the drinking behaviour of the 1958 cohort at age 33 and the 1970 cohort at age 34 [PDF]

, 2007
This paper provides a comparison of the drinking patterns of members of the 1958 British Birth Cohort at age 33 in 1991 and members of the 1970 British Birth Cohort at age 34 in 2004.
Dodgeon, Brian, Elliott, Jane, Elliott, Julian   +2 more
core   +1 more source

Systematically missing confounders in individual participant data meta-analysis of observational cohort studies. [PDF]

, 2009
One difficulty in performing meta-analyses of observational cohort studies is that the availability of confounders may vary between cohorts, so that some cohorts provide fully adjusted analyses while others only provide partially adjusted analyses ...
Amouyel, P, Arveiler, D, Assmann, G, Bauer, KA, Ben-Shlomo, Y, Benderly, M, Berglund, G, Bingham, A, Brennan, P, Brunner, E, Cantin, B, Chambless, L, Cooper, JA, Cooper, JA, Cooper, JA, Cremer, P, Curb, JD, Cushman, M, D'Agostino, R, Dagenais, GR, Danesh, J, Davey Smith, G, de Maat, MP, De Stavola, B, Despres, JP, Di Angelantonio, E, Ducimetiere, P, Elwood, PC, Engström, G, Eriksson, H, Evans, AE, Ferrieres, J, Feskens, EJ, Fibrinogen Studies Collaboration, Folsom, AR, Ford, I, Fowkes, FG, Goldbourt, U, Harald, K, Harald, K, Haverkate, F, Hedblad, B, Hense, HW, Iso, H, Jackson, D, Jousilahti, P, Jousilahti, P, Juhan-Vague, I, Kannel, WB, Kaptoge, S, Kiechl, S, Kitamura, A, Knottenbelt, C, Knottenbelt, C, Koenig, W, Kostis, JB, Lamarche, B, Lappas, G, Lee, AJ, Levy, D, Lewington, S, Loewel, H, Lowe, GD, Lowe, GD, Lowe, GD, Marchioli, R, Meade, TW, Meade, TW, Miller, GJ, Nagel, D, Naito, Y, Nyyssönen, K, Palmieri, V, Palosuo, T, Psaty, BM, Rasi, V, Rasi, V, Ridker, P, Robertson, M, Rodeghiero, F, Rodriguez, B, Rosenberg, RD, Rosengren, A, Rudnicka, A, Salomaa, V, Salomaa, V, Salonen, J, Sarwar, N, Sato, S, Schulte, H, Shepherd, J, Shipley, M, Smith, FB, Sweetnam, PM, Thompson, SG, Thompson, SG, Tofler, G, Tosetto, A, Tracy, RP, Tunstall-Pedoe, H, Tuomainen, TP, Tybjaerg-Hansen, A, Vahtera, E, Vahtera, E, Valagussa, F, Walker, M, Watson, S, White, I, White, IR, Wilhelmsen, L, Willeit, J, Wilson, AC, Wilson, PW, Wood, AM, Woodward, M, Wu, K, Yano, K, Yarnell, JW, Yeh, JL   +118 more
core   +1 more source

Cohort Profile: Cohort Hip and Cohort Knee (CHECK) study [PDF]

International Journal of Epidemiology, 2014
The Cohort Hip and Cohort Knee (CHECK) study included participants with early symptomatic osteoarthritis (OA) of the hip or knee and evaluated clinical, radiographic and biochemical variables in order to establish the course, prognosis and underlying mechanisms of early symptomatic osteoarthritis.
Wesseling, J., Boers, Maarten, Viergever, Max A, Hilberdink, Wim Kha, Lafeber, Floris Pjg, Dekker, Joost, Bijlsma, Johannes Wj   +6 more
openaire   +4 more sources