Results 101 to 110 of about 45,688,233 (408)

Regional differences in overweight: an effect of people or place? [PDF]

, 2008
Objective: To examine UK country and English regional differences in childhood overweight (including obesity) at 3 years and determine whether any differences persist after adjustment for individual risk factors.
Cole, T.J., Dezateux, C., Griffiths, L.J., Hawkins, S.S., Law, C., Millennium Cohort Study Child Health Group, The   +5 more
core  

Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes [PDF]

, 2021
Serum concentration of hepatic enzymes are linked to liver dysfunction, metabolic and cardiovascular diseases. We perform genetic analysis on serum levels of alanine transaminase (ALT), alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT ...
LifeLines Cohort Study, the VA Million Veteran Program   +1 more
core  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Associations between maternal pre-pregnancy BMI and infant striatal mean diffusivity

BMC Medicine
Background It is well-established that parental obesity is a strong risk factor for offspring obesity. Further, a converging body of evidence now suggests that maternal weight profiles may affect the developing offspring’s brain in a manner that confers ...
Aylin Rosberg, Harri Merisaari, John D. Lewis, Niloofar Hashempour, Minna Lukkarinen, Jerod M. Rasmussen, Noora M. Scheinin, Linnea Karlsson, Hasse Karlsson, Jetro J. Tuulari   +9 more
doaj   +1 more source

Cohorting to isolate asymptomatic spreaders: An agent-based simulation study on the Mumbai Suburban Railway [PDF]

arXiv, 2020
The Mumbai Suburban Railways, \emph{locals}, are a key transit infrastructure of the city and is crucial for resuming normal economic activity. To reduce disease transmission, policymakers can enforce reduced crowding and mandate wearing of masks. \emph{Cohorting} -- forming groups of travelers that always travel together, is an additional policy to ...
arxiv  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Low 5-year cumulative incidence of post-transplant lymphoproliferative disorders after solid organ transplantation in Switzerland

Swiss Medical Weekly, 2018
BACKGROUND Post-transplant lymphoproliferative disorder (PTLD) is a potentially life-threatening complication of transplantation occurring in the setting of immunosuppression and oncogenic viral infections.
Raphael E. Steiner, Robert Kridel, Emiliano Giostra, Thomas A. McKee, Rita Achermann, Nicolas J. Mueller, Oriol Manuel, Michael Dickenmann, Macé M. Schuurmans, Laurence de Leval, Thomas Fehr, Marianne Tinguely, Isabelle Binet, Sergio Cogliatti, Eugenia Haralamvieva, Michael Koller, the Swiss Transplant Cohort Study (STCS), Pierre-Yves Dietrich   +17 more
doaj   +1 more source

Alexithymic Traits and Hair Cortisol Concentrations in Pregnant Women

Frontiers in Psychiatry, 2020
IntroductionAlexithymia, a personality construct characterized by difficulties in identifying and expressing emotions, and an externally oriented thinking style, has been associated with a number of stress-related disorders, and physiological markers of ...
Jani Kajanoja, Jani Kajanoja, Jani Kajanoja, Max Karukivi, Max Karukivi, Max Karukivi, Paula Mustonen, Paula Mustonen, Noora M. Scheinin, Noora M. Scheinin, Susanna Kortesluoma, Ana João Rodrigues, Hasse Karlsson, Hasse Karlsson, Linnea Karlsson, Linnea Karlsson, Linnea Karlsson   +16 more
doaj   +1 more source

Maternal Executive Functioning, Emotional Availability and Psychological Distress During Toddlerhood: A FinnBrain Birth Cohort Study

Frontiers in Psychology, 2021
Executive functioning (EF) is one of the building blocks in parental caregiving behavior, and contextual variables have been reported to moderate the link between EF and caregiving behavior.
Elisabeth Nordenswan, Elisabeth Nordenswan, Kirby Deater-Deckard, Mira Karrasch, Matti Laine, Eeva-Leena Kataja, Eeva Holmberg, Eeva Eskola, Hetti Hakanen, Hasse Karlsson, Hasse Karlsson, Hasse Karlsson, Linnea Karlsson, Linnea Karlsson, Linnea Karlsson, Riikka Korja, Riikka Korja   +16 more
doaj   +1 more source

Artificial intelligence for diagnosing and predicting survival of patients with renal cell carcinoma: Retrospective multi-center study [PDF]

arXiv, 2023
Background: Clear cell renal cell carcinoma (ccRCC) is the most common renal-related tumor with high heterogeneity. There is still an urgent need for novel diagnostic and prognostic biomarkers for ccRCC. Methods: We proposed a weakly-supervised deep learning strategy using conventional histology of 1752 whole slide images from multiple centers.
arxiv