Results 141 to 150 of about 45,688,233 (408)

Cohort Profile: Melbourne Atopy Cohort study (MACS) [PDF]

open access: yesInternational Journal of Epidemiology, 2016
Advance Access Publication Date: 21 April 2016 ; Adrian J Lowe, Caroline J Lodge, Katrina J Allen, Michael J Abramson, Melanie C Matheson, Paul S Thomas, Christopher A Barton, Catherine M Bennett, Bircan Erbas, Cecilie Svanes, Mathias Wjst, Francisco G, omez Real, Jennifer L Perret, Melissa A Russell, Melissa C Southey, John L Hopper, Lyle C Gurrin ...
Cecilie Svanes   +24 more
openaire   +4 more sources

The effects of age on associations between markers of HIV progression and markers of metabolic function including albumin, haemoglobin and lipid concentrations. [PDF]

open access: yes, 2013
OBJECTIVES: We investigated whether age modified associations between markers of HIV progression, CD4 T lymphocyte count and HIV RNA viral load (VL), and the following markers of metabolic function: albumin, haemoglobin, high-density lipoprotein ...
Chadwick, D   +13 more
core   +4 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

6-month consequences of COVID-19 in patients discharged from hospital: a cohort study

open access: yesThe Lancet, 2023
Chaolin Huang   +31 more
semanticscholar   +1 more source

Differences in HIV clinical outcomes amongst heterosexuals in the United Kingdom by ethnicity [PDF]

open access: yes, 2021
OBJECTIVE: We investigated differences in clinical outcomes in heterosexual participants, by ethnicity in the UK Collaborative HIV Cohort Study from 2000-2017. DESIGN: Cohort analysis.
Dhairyawan, R   +4 more
core  

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

The FinnBrain multimodal neonatal template and atlas collection

open access: yesCommunications Biology
The accurate processing of neonatal and infant brain MRI data is crucial for developmental neuroscience but presents unique challenges that child and adult data do not.
Jetro J. Tuulari   +18 more
doaj   +1 more source

A general semiparametric Z-estimation approach for case-cohort studies [PDF]

open access: yesarXiv, 2012
Case-cohort design, an outcome-dependent sampling design for censored survival data, is increasingly used in biomedical research. The development of asymptotic theory for a case-cohort design in the current literature primarily relies on counting process stochastic integrals.
arxiv  

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