Results 141 to 150 of about 2,917,326 (313)

Cohort Profile: The Swiss HIV Cohort Study [PDF]

International Journal of Epidemiology, 2009
Swiss HIV Cohort Study,, Schoeni-Affolter, Franziska, Ledergerber, Bruno, Rickenbach, Martin, Rudin, Christoph, Günthard Huldrych, F., Telenti, Amalio, Furrer, Hansjakob, Yerly, Sabine, Francioli, Patrick   +9 more
openaire   +5 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Long‐term effect of caesarean section on the gut microbial taxonomical profile and metabolic function of children at pre‐school age

Clinical and Translational Medicine, 2023
Chang Gao, Dan‐Tong Shao, Cheng‐Rui Wang, Ya‐Shu Kuang, Jin‐Hua Lu, Ding‐Yuan Zeng, Jian‐Rong He, Xiu Qiu   +7 more
doaj   +1 more source

Impact of closed-off management due to COVID-19 rebound on maternal depression during pregnancy

BMC Pregnancy and Childbirth
Background This study aimed to assess the impacts of closed-off measures with different strictness levels (lockdown, partial lockdown and non-lockdown) and geographic proximity to patients with coronavirus disease 2019 (COVID-19) on prenatal depression ...
Wanqing Xiao, Yuting Yang, Huiyun Xiao, Peiyuan Huang, Dongmei Wei, Yingfang Wu, Jia Yu, Jian-Rong He, Xiu Qiu   +8 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Impact of enterococcal colonization and infection in solid organ transplantation recipients from the Swiss Transplant Cohort Study

, 2014
BACKGROUND: The burden of enterococcal infections has increased over the last decades with vancomycin-resistant enterococci (VRE) being a major health problem. Solid organ transplantation is considered as a risk factor. However, little is known about the
Khanna, N., Boggian, K, Cusini, A., Kralidis, G., Manuel, O, Kralidis, Georg, Manuel, Oriol, Garzoni, C., Bucheli, E, Manuel, O., Mueller, N.J., Kralidis, G, Berger, C., Meylan, P R A, Müller, Nicolas J, Koller, Michael T, Garzoni, C, Boggian, Katia, Cusini, Alexia, Meylan, P.R., Mueller, N J, Cusini, A, Berger, C, van Delden, C, Berger, Christoph, Boggian, K., Weisser, Maja, Koller, M.T., van Delden, C., Khanna, N, Weisser, M, Bucheli, Evelin, van Delden, Christian, Weisser, M., Koller, M T, Bucheli, E., Khanna, Nina, Garzoni, Christian, Meylan, Pascal R A   +38 more
core   +1 more source

Association of maternal blood mercury concentration during the first trimester of pregnancy with birth outcomes

Scientific Reports
Exposure to mercury has been associated with adverse effects on pregnancy outcomes. However, there is limited literature on mercury exposure and pregnancy outcomes in Chinese pregnant women.
Wei Li, Chong Miao, Bin Sun, Zhengqin Wu, Xinrui Wang, Haibo Li, Haiyan Gao, Yibing Zhu, Hua Cao   +8 more
doaj   +1 more source

Cohort Profile: The Hoorn Studies [PDF]

International Journal of Epidemiology, 2017
Rutters, F., Nijpels, G., Elders, P., Stehouwer, C.D.A., Heijden, A.A. van der, Groeneveld, L., Hart, L.M. 't, Dekker, J.M., Beulens, J.W.J.   +8 more
openaire   +3 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source