Results 161 to 170 of about 45,541,444 (388)
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Persistence of somatic symptoms after COVID-19 in the Netherlands: an observational cohort study
The Lancet, 2022 A. Ballering +3 more
semanticscholar +1 more source
Cohort Profile: The Doetinchem Cohort Study [PDF]
International Journal of Epidemiology, 2008 Verschuren, WMMrivm +3 more
openaire +4 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Risks and burdens of incident diabetes in long COVID: a cohort study
The Lancet Diabetes and Endocrinology, 2022 Yan Xie, Z. Al-Aly
semanticscholar +1 more source
Organisational justice and health of employees: prospective cohort study [PDF]
, 2003 Aims: To examine the association between components of organisational justice (that is, justice of decision making procedures and interpersonal treatment) and health of employees.Methods: The Poisson regression analyses of recorded all-cause sickness ...
Elovainio, M +3 more
core
, 2020 Background: The vast differences in sampling techniques, cultural contexts between international studies, the differences in age groups of the samples and various definitions used to measure sexting make it hard to compare how sexting behaviour has ...
Baccarne, Bastiaan +7 more
core +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source