Results 81 to 90 of about 46,993,701 (406)

Korean frailty and aging cohort study (KFACS): cohort profile

BMJ Open, 2020
Purpose The purpose of the Korean Frailty and Aging Cohort Study (KFACS) is to initiate a nationwide, population-based prospective cohort study of older adults living in the community to assess their frailty status and explore transitions between frailty
C. Won, Seoyoon Lee, Jinhee Kim, D. Chon, Sunyoung Kim, Chang-O Kim, Mi Kyung Kim, B. Cho, K. Choi, E. Roh, H. Jang, S. Son, Jin-Hee Lee, Y. Park, Sam-Gyu Lee, B. Kim, H. Kim, Jaekyung Choi, H. Ga, Kee-Jae Lee, Yunhwan Lee, Miji Kim   +21 more
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Feasibility of collecting oral fluid samples in the home setting to determine seroprevalence of infections in a large-scale cohort of preschool-aged children [PDF]

, 2009
Oral fluid is a non-invasive biological sample, which can be returned by post, making it suitable for large-scale epidemiological studies in children.
Bartington, SE, Brown, D, Dezateux, C, Joshi, H, Millennium Cohort Study Child Hlth, MM, Peckham, C   +5 more
core  

Intrapartum epidural analgesia and breastfeeding: a prospective cohort study [PDF]

, 2016
BACKGROUND Anecdotal reports suggest that the addition of fentanyl (an opioid) to epidural analgesia for women during childbirth results in difficulty establishing breastfeeding.
Ellwood, David A, Roberts, Christine L, Simpson, Judy M, Thompson, Jane F, Torvaldsen, Siranda   +4 more
core   +1 more source

Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study

Journal of Epidemiology, 2020
Background We established a community-based cohort study to assess the long-term impact of the Great East Japan Earthquake on disaster victims and gene-environment interactions on the incidence of major diseases, such as cancer and cardiovascular ...
A. Hozawa, K. Tanno, N. Nakaya, Tomohiro Nakamura, N. Tsuchiya, Takumi Hirata, A. Narita, M. Kogure, K. Nochioka, Ryohei Sasaki, Nobuyuki Takanashi, Kotaro Otsuka, K. Sakata, S. Kuriyama, M. Kikuya, Osamu Tanabe, J. Sugawara, Kichiya Suzuki, Yoichi Suzuki, Eiichi N. Kodama, N. Fuse, H. Kiyomoto, H. Tomita, A. Uruno, Yohei Hamanaka, H. Metoki, M. Ishikuro, T. Obara, Tomoko Kobayashi, K. Kitatani, Takako Takai-Igarashi, S. Ogishima, M. Satoh, H. Ohmomo, A. Tsuboi, S. Egawa, T. Ishii, K. Ito, S. Ito, Y. Taki, N. Minegishi, N. Ishii, Masao Nagasaki, K. Igarashi, S. Koshiba, R. Shimizu, G. Tamiya, K. Nakayama, H. Motohashi, J. Yasuda, A. Shimizu, Tsuyoshi Hachiya, Yuh Shiwa, T. Tominaga, Hiroshi Tanaka, K. Oyama, R. Tanaka, H. Kawame, A. Fukushima, Y. Ishigaki, T. Tokutomi, N. Osumi, Tadao Kobayashi, Fuji Nagami, Hiroaki Hashizume, Tomohiro Arai, Yoshio Kawaguchi, Shinichi Higuchi, M. Sakaida, R. Endo, S. Nishizuka, I. Tsuji, J. Hitomi, Motoyuki Nakamura, K. Ogasawara, N. Yaegashi, K. Kinoshita, S. Kure, A. Sakai, S. Kobayashi, K. Sobue, Makoto Sasaki, Masayuki Yamamoto   +82 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Associations between maternal pre-pregnancy BMI and infant striatal mean diffusivity

BMC Medicine
Background It is well-established that parental obesity is a strong risk factor for offspring obesity. Further, a converging body of evidence now suggests that maternal weight profiles may affect the developing offspring’s brain in a manner that confers ...
Aylin Rosberg, Harri Merisaari, John D. Lewis, Niloofar Hashempour, Minna Lukkarinen, Jerod M. Rasmussen, Noora M. Scheinin, Linnea Karlsson, Hasse Karlsson, Jetro J. Tuulari   +9 more
doaj   +1 more source

Interactions between cortisol and lipids in human milk

International Breastfeeding Journal, 2020
Background Human breast milk is one of the key early postnatal biological exposures for the developing child. It includes bioactive compounds, such as cortisol and fatty acids, which may be linked via the mother’s lipid metabolism.
Kaisa M. Linderborg, Maaria Kortesniemi, Anna-Katariina Aatsinki, Linnea Karlsson, Hasse Karlsson, Baoru Yang, Henna-Maria Uusitupa   +6 more
doaj   +1 more source

Maternal Alexithymic Traits Are Related to Lower Maternal Sensitivity and Higher Hostility in Maternal Caregiving Behavior—The FinnBrain Birth Cohort Study

Frontiers in Psychology, 2021
Background: The quality of parental caregiving behavior with their child plays a key role in optimal mother–infant interaction and in supporting child adaptive development.
Hanna Ahrnberg, Hanna Ahrnberg, Riikka Korja, Riikka Korja, Noora M. Scheinin, Noora M. Scheinin, Saara Nolvi, Saara Nolvi, Saara Nolvi, Eeva-Leena Kataja, Jani Kajanoja, Jani Kajanoja, Hetti Hakanen, Hetti Hakanen, Linnea Karlsson, Linnea Karlsson, Linnea Karlsson, Hasse Karlsson, Hasse Karlsson, Hasse Karlsson, Max Karukivi, Max Karukivi   +21 more
doaj   +1 more source

Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study. [PDF]

, 2015
Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding ...
D:A:D study group, ., ESPRIT study group, ., Fux, CA, INSIGHT study group, ., Johnson, MA, Kirk, O, Law, M, Lundgren, JD, Mocroft, A, Moranne, O, Morlat, P, Neuhaus, J, Reiss, P, Ross, M, Royal Free Hospital Clinic Cohort, ., Ryom, L, SMART study group, ., Smith, C, Wentworth, D   +18 more
core