Results 121 to 130 of about 876,730 (357)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Optimal Card Design for Non-Linear HF RFID Integrated Circuits With Guaranteed Standard-Compliance

open access: yesIEEE Access, 2018
The state-of-the-art design criteria for High Frequency (HF) Radio Frequency IDentification (RFID) cards at 13.56 MHz depend on the choice of a resonance frequency and a quality factor of the card.
Shrief Rizkalla   +2 more
doaj   +1 more source

Evaluation of MR angiography at 7.0 Tesla MRI using birdcage radio frequency coils with end caps [PDF]

open access: bronze, 2008
Chang‐Ki Kang   +6 more
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Establishment of the Rat Model of Intracranial Aneurysm Contributing to the Development of Endovascular Devices

open access: yesBiomedicines
Background: Endovascular treatment has become the major choice for treating intracranial aneurysm (IA). The development of novel endovascular devices for IA treatment is, therefore, socially important. For this purpose, a preclinical animal model to test
Masahiko Itani, Tomohiro Aoki
doaj   +1 more source

The Spatial Clustering of ROSAT All-Sky Survey AGN: I. The cross-correlation function with SDSS Luminous Red Galaxies

open access: yes, 2010
We investigate the clustering properties of ~1550 broad-line active galactic nuclei (AGNs) at =0.25 detected in the ROSAT All-Sky Survey (RASS) through their measured cross-correlation function with ~46,000 Luminous Red Galaxies (LRGs) in the Sloan ...
Abazajian   +41 more
core   +1 more source

Chirality of Coiled Coils: Elasticity Matters

open access: yesPhysical Review Letters, 2008
Coiled coils are important protein-protein interaction motifs with high specificity that are used to assemble macromolecular complexes. Their simple geometric organization, consisting of alpha helices wrapped around each other, confers remarkable mechanical properties.
Neukirch, S, Goriely, A, Hausrath, A
openaire   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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