Results 81 to 90 of about 410,815 (307)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Efficient Multiobjective Optimization Framework for Induction Heating Systems Design
IEEE AccessInduction heating is an efficient alternative to fuel combustion in thermal applications. The design of the coil arrangement is a complex problem, constrained by electromagnetic and thermal dynamics.
Enrico Spateri +3 more
doaj +1 more source
Ferrofluidic solenoid with axial and radial displacement [PDF]
, 1972 New design is proposed for ferrofluidic solenoid with low magnetic flux leakage. Solenoid consists of a coil centered within a football-shaped elastomeric capsule filled with a ferromagnetic fluid.
Sabelman, E. E.
core +1 more source
Design, fabrication and test of integrated micro-scale vibration based electromagnetic generator [PDF]
, 2008 This paper discusses the design, fabrication and testing of electromagnetic microgenerators. Three different designs of power generators are partially microfabricated and assembled.
Beeby +18 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Development of the Coil Spring Design Program for Spring Operating Mechanism [PDF]
한국정밀공학회지, 2017 Since the performance of the spring operating mechanism for a circuit breaker mainly depends on the dynamic behavior and mass of the coil spring, its dynamic analysis is required to evaluate the performance of the spring operating mechanism.
Min Soo Kim +2 more
doaj +1 more source
Data-Driven Prediction and Design of bZIP Coiled-Coil Interactions
PLOS Computational Biology, 2015 Selective dimerization of the basic-region leucine-zipper (bZIP) transcription factors presents a vivid example of how a high degree of interaction specificity can be achieved within a family of structurally similar proteins. The coiled-coil motif that mediates homo- or hetero-dimerization of the bZIP proteins has been intensively studied, and a ...
Vladimir Potapov +2 more
openaire +6 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Analysis of coil slumping [PDF]
, 2009 Steel strip is usually stored as a coil, which will slump to some degree after the removal of the mandrel. More often than not, the amount of slumping is so minor that it is assumed not to have occurred.
Anderssen, Bob +3 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source