Results 101 to 110 of about 32,623 (250)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Preventing Distal Coil Embolization during Coiling Occlusion of Internal Carotid Artery Pseudoaneurysm Using Partial-crushed Stent Technique

Heart Views
Hereby, we are presenting a new technique for the safe occlusion of an artery with coiling without a risk for distal coil embolization. Placing a partially crushed stent in the distal part of an artery and coiling in the mid portion of the artery can be ...
Arash Hashemi, Alireza Serati, Lida Ghaffari, Shabahang Mohammadi, Mohammad Hossein Mirbolouk, Mohammad Reza Movahed   +5 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

UMBILICAL CORD COILING AND FETAL GROWTH

, 2001
Umbilical cord coiling and fetal ...
Schneider H, RAIO L, BOLLA D, BRUHWILER H, SCHNEIDER H., GHEZZI, FABIO, Triacca P, FRANCHI, Massimo Piergiuseppe, Bruhwiler, Ghezzi F, DI NARO E, FRANCHI M   +11 more
core   +2 more sources

Corrigendum: Anterior Communicating Artery Aneurysms: Anatomical Considerations and Microsurgical Strategies

Frontiers in Neurology, 2020
Junhui Chen, Junhui Chen, Mingchang Li, Xun Zhu, Yan Chen, Chunlei Zhang, Wenwen Shi, Qianxue Chen, Yuhai Wang   +8 more
doaj   +1 more source

CXCL1: a novel therapeutic target to increase aneurysm healing after coil embolization

Frontiers in Stroke
ObjectiveCXCL1 is highly expressed in human aneurysms but its role in aneurysm healing is unknown. The objective of this study was to determine whether CXCL1 neutralization increases murine aneurysm healing post-coiling.MethodsCarotid artery aneurysms ...
Devan Patel, Devan Patel, Melanie Martinez, Supreeya A. Saengchote, Kartik Motwani, William S. Dodd, Zahra Hasanpour Segherlou, Haiyan Xu, Koji Hosaka, Brian L. Hoh   +9 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source