Results 21 to 30 of about 22,504 (264)

Design of a heterotetrameric coiled coil [PDF]

Protein Science, 2009
AbstractWe have successfully designed a simple peptide sequence that forms highly stable coiled‐coil heterotetramers. Our model system is based on the GCN4‐pLI parallel coiled‐coil tetramer, first described by Kim and coworkers (Harbury et al., Science 1993;262:1401–1407). We introduced glutamates at all of the e and c heptad positions of one sequence (
Benjamin C, Root, Laurel D, Pellegrino, Emily D, Crawford, Bashkim, Kokona, Robert, Fairman   +4 more
openaire   +2 more sources

TCMacro: A Simple and Robust ImageJ-Based Method for Automated Measurement of Tail Coiling Activity in Zebrafish

Biomolecules, 2021
Tail coiling is a reflection response in fish embryos that can be used as a model for neurotoxic analysis. The previous method to analyze fish tail coiling is largely based on third-party software.
Kevin Adi Kurnia, Fiorency Santoso, Bonifasius Putera Sampurna, Gilbert Audira, Jong-Chin Huang, Kelvin H.-C. Chen, Chung-Der Hsiao   +6 more
doaj   +1 more source

Coiled‐coils: The long and short of it [PDF]

BioEssays, 2016
Coiled‐coils are found in proteins throughout all three kingdoms of life. Coiled‐coil domains of some proteins are almost invariant in sequence and length, betraying a structural and functional role for amino acids along the entire length of the coiled‐coil.
Truebestein, Linda, Leonard, Thomas A.
openaire   +2 more sources

Hemodynamic Effect of the Last Finishing Coils in Packing the Aneurysm Neck

Frontiers in Neurology, 2020
Background: Using the finishing coils to densely pack the aneurysm neck is necessary. However, the exact hemodynamic effect of finishing coils in packing the aneurysm neck is unknown.Objective: To evaluate the hemodynamic characteristics of finishing ...
Hailin Wan, Gang Lu, Lei Huang, Liang Ge, Yeqing Jiang, Gaohui Li, Xiaochang Leng, Jianping Xiang, Xiaolong Zhang   +8 more
doaj   +1 more source

TARGET® Intracranial Aneurysm Coiling Prospective Multicenter Registry: Final Analysis of Peri-Procedural and Long-Term Safety and Efficacy Results

Frontiers in Neurology, 2019
Background and Purpose: To describe the final results of the TARGET Registry, a multicenter, real-world study of patients with intracranial aneurysms treated with new generation TARGET Coils.Methods: The TARGET Registry is a prospective, single-arm study
Osama O. Zaidat, Alicia C. Castonguay, Ansaar T. Rai, Aamir Badruddin, William J. Mack, Amer K. Alshekhlee, Qaisar A. Shah, Syed I. Hussain, Mouhammed R. Kabbani, Ketan R. Bulsara, Asif M. Taqi, Vallabh Janardhan, Mary S. Patterson, Brittany L. Nordhaus, Lucas Elijovich, Ajit S. Puri   +15 more
doaj   +1 more source

Is a thin diameter ureteroscope feasible for image guided intravascular procedures?

Current Directions in Biomedical Engineering, 2020
Vascular endoscopic imaging is known for a long time but has never made its way into clinical routine. Reasons for that are the complexity, lack of low-cost portable systems, and the lack of suitable endoscopes providing high image quality with small ...
Boese Axel, Friebe Michael
doaj   +1 more source

Intrasaccular Flow Disruptor-Assisted Coiling of Intracranial Aneurysms Using the Novel Contour Neurovascular Systems and NEQSTENT: A Single-Center Safety and Feasibility Study

Brain Sciences, 2022
Background: Intrasaccular flow disruptors (IFD) have been introduced in the treatment of intracranial aneurysms (IAs) to overcome the low aneurysm occlusion rate and the high recanalization rate of the coiling technique.
Francesco Diana, Marta de Dios Lascuevas, Simone Peschillo, Eytan Raz, Shinichi Yoshimura, Manuel Requena Ruiz, David Hernández Morales, Alejandro Tomasello   +7 more
doaj   +1 more source

Comparison of angiographic outcomes and complication rates of WEB embolization and coiling for treatment of unruptured basilar tip aneurysms

Scientific Reports, 2022
Endovascular coiling represents the standard treatment for basilar tip aneurysms. Some of these aneurysms are not amenable to conventional coiling due to a complex aneurysm geometry, hence, novel devices such as the Woven Endobridge (WEB) have been ...
Erkan Celik, Yigit Ozpeynirci, Thomas Liebig, Marc Schlamann, Franziska Dorn, Nils Lehnen, Eberhard Siebert, Lukas Goertz, Christoph Kabbasch   +8 more
doaj   +1 more source

Radiological outcomes for endovascular treatment of posterior communicating artery aneurysms: a retrospective multicenter study of the occlusion rate

Journal of Integrative Neuroscience, 2021
Although several innovations in techniques and implantable devices were reported over the last decades, a consensus on the best endovascular treatment for intracranial aneurysms originating from the posterior communicating artery is still missing.
Alba Scerrati, Gianluca Trevisi, Carmelo Lucio Sturiale, Francesco Salomi, Pasquale De Bonis, Andrea Saletti, Annunziato Mangiola, Alberto Tomatis, Vincenzo Di Egidio, Vera Vigo, Alessandro Pedicelli, Iacopo Valente, Oriela Rustemi, Giacomo Beggio, Giuseppe Iannucci, Luca Milonia, Luca Ricciardi, Amedeo Cervo, Guglielmo Pero, Mariangela Piano   +19 more
doaj   +1 more source

Endovascular Management of Cerebral Aneurysm: The Recent Trends

Indian Journal of Neurosurgery, 2018
Cerebral aneurysm rupture is the leading cause of mortality and morbidity in patients with hemorrhagic stroke. Surgical clipping and endovascular coiling are the mainstay of management for securing the aneurysm.
Vipul Gupta, Shrikant Londhe, Rajsrinivas Parthasarathy, Hilal Ahmad Ganaie   +3 more
doaj   +1 more source