Results 71 to 80 of about 36,323 (288)

Solvability of fractional-order multi-point boundary-value problems at resonance on the half-line

open access: yesElectronic Journal of Differential Equations, 2012
In this article, we study a fractional differential equation. By constructing two special Banach spaces and establishing an appropriate compactness criterion, we present some existence results about the boundary-value problem at resonance via Mawhin's
Yi Chen, Zhanmei Lv
doaj  

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Coincidence conditions in multifaciity location problems with positive and negative weights [PDF]

open access: yes, 1998
In minisum multifacility location problems one has to find locations for some new facilities, such that the weighted sum of distances between the new and a certain number of old facilities with known locations is minimized.
Fliege, Jorg
core   +1 more source

Ambrosetti–Prodi Periodic Problem Under Local Coercivity Conditions

open access: yesAdvanced Nonlinear Studies, 2018
In this paper we focus on the periodic boundary value problem associated with the Liénard differential equation x′′+f⁢(x)⁢x′+g⁢(t,x)=s{x^{\prime\prime}+f(x)x^{\prime}+g(t,x)=s}, where s is a real parameter, f and g are continuous functions and g is T ...
Sovrano Elisa, Zanolin Fabio
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Coincidence of high antiislet and antithyroid autoantibody titles in first-degree relatives of patients with type 1 diabetes [PDF]

open access: yes, 2005
An association between thyroid and islet autoantibodies has been reported for patients with type 1 diabetes and their first-degree relatives. However no general agreement on this association has been reached since several studies reported controversial ...
Sougioultzoglou F.   +5 more
core   +1 more source

New results on periodic solutions of delayed Nicholson's blowflies models

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2012
This paper is concerned with a class of Nicholson's blowflies models with a nonlinear density-dependent mortality term. We use coincidence degree theory and give several sufficient conditions which guarantee the existence of positive periodic solutions ...
Xinhua Hou, Lian Duan
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Periodic solutions for a neutral delay predator-prey model with nonmonotonic functional response

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2012
By using a continuation theorem based on coincidence degree theory, some new sufficient conditions are obtained for the existence of positive periodic solutions of the following neutral delay predator-prey model with nonmonotonic functional response ...
Lian Duan
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

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