Results 61 to 70 of about 422,657 (323)

The dimensionless age of the Universe: a riddle for our time

, 2016
We present the interesting coincidence of cosmology and astrophysics that points toward a dimensionless age of the universe H_0*t_0 that is close to one.
Avelino, Arturo, Kirshner, Robert P.
core   +1 more source

Existence of a solution for a nonlinear integral equation by nonlinear contractions involving simulation function in partially ordered metric space

Nonlinear Analysis, 2023
In a recent paper, Khojasteh et al. presented a new collection of simulation functions, said Z-contraction. This form of contraction generalizes the Banach contraction and makes different types of nonlinear contractions.
Parvaneh Lo'Lo', Maryam Shams, Manuel De la Sen   +2 more
doaj   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Event coincidence analysis for quantifying statistical interrelationships between event time series: on the role of flood events as possible triggers of epidemic outbreaks

, 2016
Studying event time series is a powerful approach for analyzing the dynamics of complex dynamical systems in many fields of science. In this paper, we describe the method of event coincidence analysis to provide a framework for quantifying the strength ...
Donges, Jonathan F., Donner, Reik V., Schleussner, Carl-Friedrich, Siegmund, Jonatan F.   +3 more
core   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Variation of Fixed-Point and Coincidence Sets [PDF]

Journal of the Australian Mathematical Society. Series A. Pure Mathematics and Statistics, 1988
AbstractTopologise the set of continuous self-mappings of a Hausdorff space by the graph topology. When the set of closed subsets of the space is given the upper semi-finite topology then the function which assigns to a map its fixed-point set is continuous. In many familiar cases this is the largest such topology.
openaire   +3 more sources

Tripled Coincidence Points of Mappings in Partially Ordered 0-Complete Partial Metric Spaces

International Journal of Analysis and Applications, 2013
In this paper, we introduce the concept of a tripled coincidence point for a pair of nonlinear contractive mappings F : X3 → X and g : X → X in partially ordered 0-complete partial metric spaces and obtain existence and uniqueness theorems.
Vesna Cojbasic Rajic
doaj   +2 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

The least number of coincidence points on surfaces [PDF]

Journal of the Australian Mathematical Society. Series A. Pure Mathematics and Statistics, 1995
AbstractBo Ju Jiang introduced an invariant lying in the braid group which is the best lower bound of the number of fixed points in a homotopy class of a given pair of self maps of a surface. Here we modify this construction to get a lower bound of the number of coincidence points of a pair of maps between two closed surfaces.
openaire   +3 more sources

Coordinates, observables and symmetry in relativity

, 2009
We investigate the interplay and connections between symmetry properties of equations, the interpretation of coordinates, the construction of observables, and the existence of physical relativity principles in spacetime theories. Using the refined notion
Anderson, Barbour, Bergmann, Bluman, Brown, Brown, Brown, Cantwell, DeWitt, Dittrich, Dittrich, Earman, Earman, Einstein, Einstein, Einstein, Einstein, Ferrario, Friedman, Giulini, Hans Westman, Hawking, Ibragimov, Ibragimov, Ibragimov, Ibragimov, Iftime, Kiefer, Kretschmann, Kuchar, Misner, Norton, Olver, Rovelli, Rovelli, Sebastiano Sonego, Sorkin, Stachel, Stachel, Varadarajan, Wald, Westman   +41 more
core   +2 more sources