Results 171 to 180 of about 32,253 (335)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

The impact of expectant management compared with intrauterine insemination with ovarian stimulation on quality of life and coital frequency in couples with unexplained subfertility. [PDF]

F S Rep
Wessel JA, Mochtar MH, van Eekelen R, Louwé LA, Kaaijk EM, Goddijn M, van Wely M, Mol F.   +7 more
europepmc   +1 more source

The Amoral Approach to Sex Counselling of Collegians [PDF]

, 1968
Murphy, Daniel P.
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Impact of Infertility and Medically Assisted Reproduction Treatments on Female Sexuality. [PDF]

JBRA Assist Reprod
Bannour B, Salem D, Bannour R, Saad OKB, Bannour I.   +4 more
europepmc   +1 more source

The Teaching of Pope Pius XII on Artificial Insemination [PDF]

, 1956
Kelly, Gerald
core   +1 more source

THE RATE OF SPERM PASSAGE INTO THE CERVIX AFTER COITUS IN THE RABBIT [PDF]

, 1971
J. M. Bedford
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Serum level of soluble Interleukin-2 receptor among human papilloma virus infected female patients. [PDF]

Infect Agent Cancer
Yasin MM, Hassan RA, El Sayed AA, Ezzelarab SS, Helal MM, Abdelhady AS.   +5 more
europepmc   +1 more source

Male Spine Motion During Coitus

, 2014
Natalie Sidorkewicz, Stuart M. McGill
openalex   +2 more sources