Tumor FAK supports fibrillar collagen expression in ovarian cancer ascites. [PDF]
Ojalill M +11 more
europepmc +1 more source
Farnesoid X Receptor Agonist INT‐787 Protects Human Liver Organoids From Alcohol‐Induced Injury
ABSTRACT Background Alcohol‐associated liver disease (ALD) represents a spectrum of liver injury ranging from steatosis to alcohol‐associated hepatitis, cirrhosis, and hepatocellular carcinoma. Activation of the farnesoid X receptor (FXR) decreases liver steatosis, inflammation, and fibrosis in animal models of liver‐related diseases, including ...
Francesca De Franco +8 more
wiley +1 more source
Integrative Bioinformatics and Exploratory Experimental Validation of Expression Changes in miR-214-3p, miR-1b, miR-133b-3p, and Directionally Concordant mRNAs in a Rat Model of Acute Myocardial Infarction. [PDF]
Yamasan BE, Yıldız M, Korkmaz S.
europepmc +1 more source
COL3A1 Variants in Spontaneous Coronary Artery Dissection
Lucy McGrath-Cadell +8 more
openaire +2 more sources
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Gene Expression of <i>TGF-β1</i>, Matrix Metalloproteinases, and Collagen in Keloid Patients and Their Growth Patterns in 2D and 3D Cell Cultures: An <i>In Vitro</i> Study. [PDF]
Helmer A +8 more
europepmc +1 more source
Abstract Nodular fasciitis (NF) is a benign myofibroblastic neoplasm characterized by rapid growth and recurrent USP6 rearrangements. Despite its benign nature, NF may exhibit worrisome histologic or clinical features that mimic sarcoma, posing diagnostic challenges.
Kristijan Skok +6 more
wiley +1 more source
Pregnancy Outcomes in Women With Vascular Ehlers-Danlos Syndrome: A Systematic Review of Maternal and Fetal Complications. [PDF]
Almheiri S, ElMubarak A, Fadlalsaed O.
europepmc +1 more source
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat +14 more
wiley +1 more source
ABSTRACT Hydrocalumite‐like phases, belonging to the layered double hydroxide family, are potential biomaterials for bone repair; however, their cellular effects remain incompletely understood. Here, we evaluated a hydrocalumite‐like material of composition [Ca2Al(OH)₆]Cl·nH2O (abbreviated Ca2Al–Cl) in preosteoblastic MC3T3‐E1 cells, assessing ...
C. J. da Costa Fernandes +4 more
wiley +1 more source

