Results 171 to 180 of about 21,356 (260)

Tumor FAK supports fibrillar collagen expression in ovarian cancer ascites. [PDF]

open access: yesMatrix Biol
Ojalill M   +11 more
europepmc   +1 more source

Farnesoid X Receptor Agonist INT‐787 Protects Human Liver Organoids From Alcohol‐Induced Injury

open access: yesLiver International Communications, Volume 7, Issue 4, December 2026.
ABSTRACT Background Alcohol‐associated liver disease (ALD) represents a spectrum of liver injury ranging from steatosis to alcohol‐associated hepatitis, cirrhosis, and hepatocellular carcinoma. Activation of the farnesoid X receptor (FXR) decreases liver steatosis, inflammation, and fibrosis in animal models of liver‐related diseases, including ...
Francesca De Franco   +8 more
wiley   +1 more source

COL3A1 Variants in Spontaneous Coronary Artery Dissection

open access: yesJACC: Advances
Lucy McGrath-Cadell   +8 more
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, Volume 20, Issue 11, Page 2569-2583, November 2026.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The molecular landscape of nodular fasciitis: novel USP6 fusions, genomic stability, and an exploratory clinicopathological model – a 20‐year retrospective study

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 6, November 2026.
Abstract Nodular fasciitis (NF) is a benign myofibroblastic neoplasm characterized by rapid growth and recurrent USP6 rearrangements. Despite its benign nature, NF may exhibit worrisome histologic or clinical features that mimic sarcoma, posing diagnostic challenges.
Kristijan Skok   +6 more
wiley   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

open access: yesArthritis &Rheumatology, Volume 78, Issue 11, Page 2246-2260, November 2026.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat   +14 more
wiley   +1 more source

Hydrocalumite‐Like Material Induces Early Osteogenic Priming and ECM Remodeling Without Effective Mineralization in Preosteoblasts

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 11, November 2026.
ABSTRACT Hydrocalumite‐like phases, belonging to the layered double hydroxide family, are potential biomaterials for bone repair; however, their cellular effects remain incompletely understood. Here, we evaluated a hydrocalumite‐like material of composition [Ca2Al(OH)₆]Cl·nH2O (abbreviated Ca2Al–Cl) in preosteoblastic MC3T3‐E1 cells, assessing ...
C. J. da Costa Fernandes   +4 more
wiley   +1 more source

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