Results 151 to 160 of about 21,356 (260)

Elevated expression of COL3A1 and COL5A1 in muscle-invasive bladder tumors and metatstatic T24 cells.

, 2013
A. Immunohistochemistry of bladder tumors. DAB (brown) staining represents COL3A1 protein expression, while Warp Red staining represents COL5A1. Results are representative of five independent sample tissues per grade. B.
William A. Ricke (279015), Jonathan A. Ewald (279012), Tracy M. Downs (279013), Jeremy P. Cetnar (279014)   +3 more
core   +1 more source

Human Embryonic Stem Cell‐Derived Immunity‐And‐Matrix‐Regulatory Cells Attenuate Pulmonary Fibrosis via MMP1‐Mediated Collagen Degradation

Cell Proliferation, EarlyView.
Human embryonic stem cell‐derived Immunity‐and‐Matrix‐Regulatory Cells (IMRCs) effectively attenuate pulmonary fibrosis by secreting Matrix Metalloproteinase‐1 (MMP1), which directly degrades excess collagen I in the extracellular matrix. By directly degrading collagen I, IMRCs reverse ECM stiffness, suppress myofibroblast activation, and promote a ...
Zhongwen Li, Dingyun Song, Faguo Sun, Licheng Song, Bin An, Tingting Gao, Jingjing Liu, Kan Zhang, Kaidi Liu, Kaiwei Wu, Yajing Li, Yi Yang, Yaru Liu, Ruofan Su, Zai Wang, Tiemei Zhao, Huaiyong Chen, Li Xiao, Liang Peng, Liu Wang, Wei Li, Lixin Xie, Jie Hao, Huaping Dai, Jun Wu   +24 more
wiley   +1 more source

COL3A1 Gene Product [PDF]

, 2020
openaire   +1 more source

Decreased Col3a1 mRNA expression after stopping Ang II infusion, increased Collagen III protein levels.

, 2015
Col3a1 mRNA (A) and Collagen III protein (B) expression was increased under Ang II infusion. Eight weeks after stopping infusion with Ang II, mRNA levels of Col3a1 decreased to control levels.
Anne-Roos S. Frenay (752766), Anne Marijn van der Graaf (480821), Harry van Goor (18163), Saleh Yazdani (297333), Miriam Boersema (534157), Femke Waanders (752767), Gerjan J. Navis (153097), Jacob van den Born (167146)   +7 more
core   +1 more source

Repositioning Non‐Ablative Fractional Lasers ‐ Molecular and Histological Insights from a scoping review

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Near‐infrared non‐ablative fractional lasers (NAFL) are established for skin rejuvenation and scar treatment and have attracted interest for their expanding therapeutic potential. This scoping review aims to revisit and reposition NAFL within a fluence‐dependent continuum of tissue modulation, based on evidence from 27 studies of lasers ...
Guy Erlich, Uwe Paasch, Kevin Jacobsen, Merete Haedersdal, Uffe Høgh Olesen   +4 more
wiley   +1 more source

High‐resolution spatial transcriptomic atlas of mouse soleus muscle: Unveiling single cell and subcellular heterogeneity in health and denervation

The FEBS Journal, EarlyView.
Seq‐Scope maps skeletal muscle transcriptomes at high spatial resolution while preserving histological context, revealing distinct responses of myofibers, neuromuscular junctions, and stromal cells to denervation. This spatial view uncovers fiber type‐specific and localized remodeling across intact muscle tissue.
Jer‐En Hsu, Lloyd Ruiz, Yongha Hwang, Steve D. Guzman, Chun‐Seok Cho, Weiqiu Cheng, Yichen Si, Peter Macpherson, Angelo Anacleto, Qingyang Zhao, Xiaoya Zhao, Mitchell Schrank, Goo Jun, Hyun Min Kang, Myungjin Kim, Susan V. Brooks, Jun Hee Lee   +16 more
wiley   +1 more source

Purification and characterization of recombinant human type III collagen (COL3A1) fragment (C9)

Journal of Biomaterials Science, Polymer Edition
Collagen, a key structural component of the extracellular matrix (ECM), plays a critical role in tissue repair and regeneration. Compared to traditional animal-derived collagen, recombinant collagen presents enhanced safety and uniformity, avoiding immunogenicity and pathogen transmission.
Beiping Su, Zhenlin Tang, Jiaxin Duan, Zonglin Wang, Xinhe Huang   +4 more
openaire   +2 more sources

Tumour deposits are associated with increased metastatic risk in colorectal cancer: a population‐based analysis of metastatic patterns and burden

Histopathology, EarlyView.
In this population‐based cohort of 3505 patients with colorectal cancer without distant metastases at diagnosis, tumour deposits are independently associated with an increased risk of distant metastases (HR 1.34, 95% CI 1.03–1.74). This finding supports consideration of tumour deposits in future risk stratification strategies.
Yao Shu, Nelleke P M Brouwer, Marloes A G Elferink, Johannes H W de Wilt, Femke Simmer, Iris D Nagtegaal   +5 more
wiley   +1 more source

Pediatric pulmonary hemorrhage observed in non-vascular and vascular Ehlers–Danlos syndrome

Orphanet Journal of Rare Diseases
Background Ehlers–Danlos syndrome (EDS) is a heterogeneous group of heritable connective tissue disorders with varying features depending on the EDS subtype. EDS is associated with various respiratory manifestations.
Rong Yang, Haiming Yang, Chen Shen, Xingfeng Yao, Jinrong Liu, Huimin Li, Shunying Zhao   +6 more
doaj   +1 more source

PLAG1‐rearranged paediatric fibromyxoid tumour: clinicopathological, molecular and epigenetic analysis of 10 cases supporting a morphological spectrum with lipoblastoma

Histopathology, EarlyView.
P‐FMT histologically resembles fibroblastic lipoblastoma and has similar gene fusions, DNA methylation profiles, and benign clinical behaviour, supporting classification of P‐FMT as a morphological variant of lipoblastoma. Aim Paediatric PLAG1‐rearranged fibromyxoid tumour (P‐FMT) is an emerging soft‐tissue neoplasm characterized by predominantly ...
Faizan Malik, Selene C Koo, Quynh T Tran, Carina A Dehner, Robert E Ruiz, Meera Hameed, Anthony Arnoldo, Robert Siddaway, Brent A Orr, Rose Chami   +9 more
wiley   +1 more source