Results 141 to 150 of about 21,356 (260)

Hemoperitoneum Due to Dissection and Rupture of the Superior Mesenteric Artery in a Patient With COL3A1 Mutation

Academic Forensic Pathology
Introduction: Vascular Ehlers-Danlos syndrome (vEDS) is an autosomal dominant disorder that results from mutations in the collagen type III gene. It is a risk factor for medium-sized artery aneurysms, dissections, and ruptures. We report a case of hemoperitoneum due to medial dissection and rupture of the superior mesenteric artery related to vEDS ...
Fabio Tironi, Wijesinghe Lakmali, Jayantha Herath   +2 more
openaire   +3 more sources

Diagnosis of vascular Ehlers-Danlos syndrome in Italy: clinical findings and novel COL3A1 mutations.

, 2011
In this study, we describe the clinical features, the behaviour of dermal fibroblasts type III collagen (COLLIII) and COL3A1 gene mutations in 22 Italian vEDS ...
CALZAVARA PINTON, Piergiacomo, Buscemi L, Viglio S, RITELLI, Marco Giuseppe, COLOMBI, Marina, Valli M, Tadini G, Clementi M, Penco S, Danesino C, ZOPPI, Nicoletta, Nicolazzi MA, Musumeci A, VENTURINI, Marina, Wischmeijer A, BARLATI, Sergio, Crivelli S, Drera B   +17 more
core   +1 more source

Mapping the Tissue Architecture and Endothelial‐PEC Network in HAML Using Single‐Cell and Spatial Transcriptomics

Cancer Science, EarlyView.
Spatial multi‐omics mapping of hepatic angiomyolipoma reveals that PEComas tightly co‐localize with endothelial cells, which drive autophagic flux in adjacent tumor cells via a paracrine PDGFD–PDGFRB–Ras axis, establishing a compensatory survival network that operates in parallel to canonical TSC–mTOR defects.
Xinyang Liu, Yang Guo, Xuehong Tie, Yu Liu, Fuyu Li, Jingkai Liu, Xiaohang Sun, Jiajun Zhao, Feng Geng, Yingjian Liang   +9 more
wiley   +1 more source

COL3A1 Gene [PDF]

, 2020
openaire   +1 more source

A Multicellular Coordinated Network Driving Lymphovascular Space Invasion in Endometrioid Endometrial Carcinoma

Cell Proliferation, EarlyView.
Single‐cell and spatial profiling reveal that lymphovascular space invasion in endometrioid endometrial carcinoma is driven by coordinated interactions among metastatic epithelium, fibroblasts, immune cells, and endothelium. This multicellular network promotes matrix remodelling, angiogenesis, and immune evasion, forming a pro‐metastatic niche that ...
Wendi Guo, Tianxiang Liu, Runling Ren, Na Li, Wenwen Zhang, Jingwen Si, Yongjun Piao, Yuanjing Hu   +7 more
wiley   +1 more source

COL3A1 wt Allele [PDF]

, 2020
openaire   +1 more source

Genes associated with COL1A2, COL3A1, MMP9 and MMP2 as determined by NetworkAnalyst.

, 2016
The NetworkAnalyst program data reveals the genes interconnected with our genes of interest (COL1A2, COL3A1, MMP9 and MMP2) based on the published data base and the gene symbols are based on official gene symbol.
Devendra K. Agrawal (312523), Chandra S. Boosani (3589970), Matthew F. Dilisio (3281061), Finosh G. Thankam (3281058), Nicholas E. Dietz (3281055)   +4 more
core   +1 more source

Single‐Cell and Spatial Analysis Reveal the Differences Between Left‐Sided and Right‐Sided Colorectal Cancer

Cell Proliferation, EarlyView.
Single‐cell and spatial analysis revealed distinct CRC microenvironments by tumour laterality. Right‐sided tumours showed enhanced germinal centre B cells, CXCL13+ T cells, and organized TLS‐immune crosstalk via CCL19/21‐CCR7, suggesting better immunotherapy response.
Zongnai Zhang, Jiaqi Xu, Yingchao Wu, Tao Liu, Junling Zhang, Mai Zhou, Jie Qiao, Heng Pan, Xin Wang   +8 more
wiley   +1 more source

Identification and Structural Characterization of a Novel COL3A1 Gene Duplication in a Family With Vascular Ehlers–Danlos Syndrome

Molecular Genetics & Genomic Medicine
Background Vascular Ehlers–Danlos syndrome (vEDS) is caused by alterations in the COL3A1 gene, typically involving missense variants that replace glycine residues.
Gianmaria Miolo, Piernicola Machin, Marco De Conto, Sara Fortuna, Simona Viglio, Lara Della Puppa, Silvano Geremia, Giuseppe Corona   +7 more
doaj   +1 more source

Identification of COL3A1, PLAU, and SPP1 as Key Biomarkers for Early Detection of Esophageal Cancer

International Journal of Molecular Sciences
Esophageal cancer (EC) is a highly lethal malignancy often diagnosed at advanced stages due to the lack of effective early diagnostic markers. This study aimed to identify molecular markers and construct a diagnostic model for early-stage esophageal cancer using bioinformatics approaches.
Hong Zhang, Xin Cheng, Mengdi Zhang, Yixin Zuo, Shilu Zhu, Zhaorui Zuo, Xingliang Wang, Shan Lu, Xuan Gao   +8 more
openaire   +3 more sources