Results 121 to 130 of about 21,356 (260)
Arthritis &Rheumatology, Accepted Article.Objective We previously showed that Semaphorin4A (Sema4A) is elevated in patients with systemic sclerosis (SSc) and promotes inflammation and fibrosis in vitro. Here, we examined the effect of Sema4A neutralization in vivo and in 3D fibrosis models. Methods Sema4A plasma levels were measured by ELISA in healthy controls (n=31) and patients with SSc (n=
Jaime Marty +21 more
wiley +1 more source
BMEMat, EarlyView.This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu +9 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective A significant proportion of individuals with suspected genetic developmental and epileptic encephalopathies (DEEs) remain unsolved following whole genome sequencing (WGS). Here we describe biallelic RNU2‐2 variants causing a recently reported, severe, recessive DEE.
Olivia J. Henry +23 more
wiley +1 more source
Cajal-Retzius cells and interneurons are found in ectopias of Col3a1−/− mice.
, 2013 (A and B) Double IHC of Reelin (green) and laminin (red) at E16.5 showed Reelin+ CR cells are lined up beneath the pial BM in Col3a1+/+ (A) but were located within the ectopia of Col3a1−/− mice (B, arrowheads). (C and D) Immunostaining of Calbindin (red)
Rong Luo (187167) +4 more
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C to T polymorphism in exon 33 of the COL3A1 gene [PDF]
Nucleic Acids Research, 1991 G, Tromp +3 more
openaire +2 more sources
Enforced expression of miR-29b decreased Col1a1, Col3a1, and α-SMA expression.
, 2013 A. Col1a1, Col3a1, and α-SMA mRNA expression by quantitative real-time PCR assay. *p < 0.05, # p < 0.01, # # p < 0.001 vs. control group, N = 3–5. B. Col1a1, Col3a1, and α-SMA protein expression by Western-blot assay. NC, scrambled oligonucleotide.
Qiu-Xiong Lin (356999) +13 more
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iMetaOmics, EarlyView.Single‐nucleus RNA sequencing and functional profiling of goat ovaries with divergent litter sizes revealed prolificacy‐associated granulosa cell (GC) states characterized by enhanced proliferation‐ and steroidogenesis‐related features, together with altered predicted cell–cell communication.
Sanbao Zhang +6 more
wiley +1 more source
Cellular composition of Col3a1−/− cortical ectopias.
, 2013 (A, B) Cux1 antibody immunostaining revealed that the ectopias were composed in part by upper layer cortical neurons inappropriately migrating through the marginal zone in Col3a1−/− brain (arrowheads).
Rong Luo (187167) +4 more
core +1 more source
Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review
Journal of Applied Toxicology, EarlyView.ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli +5 more
wiley +1 more source
HUBUNGAN EKSPRESI GEN WT1 DAN TIMP3 TERHADAP RASIO TRANSKRIP GEN COLLAGEN TYPE 1 ALPHA 1 (COL1A1) DENGAN COLLAGEN TYPE 3 ALPHA 1 (COL3A1) PADA PASIEN ANAK DENGAN HERNIA INGUINALIS UNILATERAL [PDF]
Hernia adalah penonjolan kantong abnormal dari celah di dinding abdomen, bisa disebabkan oleh kelainan struktural kongenital atau kelainan jaringan ikat.
Jon, Efendi
core +1 more source