Results 131 to 140 of about 21,356 (260)
, 2012 Sequence alignment file (.fasta) presenting sequencing results of five T. truncatus individuals of the DNA pool for the collagen type III alpha 1-like gene (COL3A1). There is one SNP in this fragment. Four individuals were sampled in the Gulf of Mexico
Nicole L. Vollmer (3246936) +3 more
core +1 more source
Small, EarlyView.By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo +15 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Hyperlipidemia‐related erectile dysfunction (HLED) responds poorly to first‐line treatments such as phosphodiesterase type 5 inhibitors (PDE5Is), emphasizing the need for alternative therapeutic strategies. Rutaecarpine (RUT), a bioactive alkaloid, exhibits significant anti‐inflammatory and anti‐fibrotic effects.
Bocheng Tu +9 more
wiley +1 more source
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.This review quantifies the association between collagenopathies and spontaneous preterm birth, assessing their role in antenatal risk assessment. Marfan syndrome is significantly associated with an increased risk of spontaneous preterm birth (OR 2.71, 95% CI 2.23–3.30; p < 0.001; I2 = 41%) while evidence for Ehlers–Danlos syndrome is heterogeneous ...
Kensie Treacy +3 more
wiley +1 more source
Stem Cell ResearchVascular Ehlers-Danlos Syndrome (vEDS) is an inherited connective tissue disorder caused by COL3A1 gene, mutations that encodes type III collagen, a crucial component of blood vessels.
Amit Manhas +8 more
doaj +1 more source
, 2019 Table S2. Distribution of clinicopathological characteristics 645 in relation to COL3A1, GPR158 and PITHD1 protein expression.
Szilรกrd Nemes (5618741) +9 more
core +1 more source
Acta Ophthalmologica, EarlyView.Abstract A healthy tear film is vital for ocular surface integrity and relies on the coordinated function of the lacrimal glands, meibomian glands and conjunctival goblet cells. Dysfunction in any of these elements can lead to dry eye disease (DED). This systematic review and meta‐analysis evaluated the efficacy of low‐level light therapy (LLLT) as a ...
Sjur Reppe +6 more
wiley +1 more source
, 2019 (A) Col3a1/GAPDH ratio. (B) Col5a1/GAPDH ratio. In all analyses, GAPDH was used as a housekeeping gene.
Yuki Miyazaki (290900) +14 more
core +1 more source
Brain Pathology, EarlyView.Brain metastasis‐associated fibroblasts are active stromal components of the metastatic niche characterised by extracellular matrix remodelling and production of pro‐migratory mediators. They promote monocyte and cancer cell migration and enhance cancer cell invasion while having no growth‐promoting effect on cancer cells.
Barbora Výmolová +19 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo +4 more
wiley +1 more source