Results 211 to 220 of about 50,322 (265)

Gout therapy updated. [PDF]

open access: yesTher Adv Musculoskelet Dis
McCarty KL, Gaffo AL, Diaz-Torne C.
europepmc   +1 more source
Some of the next articles are maybe not open access.

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Colchicine today

Joint Bone Spine, 2006
Colchicine is used chiefly in the treatment of gout but is also valuable in other inflammatory diseases such as familial Mediterranean fever (FMF). Three proteins play pivotal roles in colchicine pharmacokinetics: the colchicine receptor, tubulin, which governs the plasma elimination half-life of the drug; intestinal and hepatic CYP3A4, which is key to
Elisabeth, Niel, Jean-Michel, Scherrmann
openaire   +2 more sources

Colchicine Revisited

Annals of the New York Academy of Sciences, 2009
Purified from a Mediterranean plant nearly two centuries ago, colchicine has been discovered to inhibit many steps in the inflammatory process. The drug has good oral bioavailability and some enterohepatic recirculation, requiring dose adjustments for kidney disease and avoidance in liver disease. Toxicities are primarily gastrointestinal, hepatic, and
Anupama, Bhat   +3 more
openaire   +2 more sources

Colchicine Neuromyopathy

JCR: Journal of Clinical Rheumatology, 1996
Colchicine myopathy can complicate standard treatment of gout, especially in those patients with underlying renal insufficiency. The symptoms of this disorder are frequently insidious, and the diagnostic tests used in its evaluation are mostly nonspecific.
D S, Uri, M, Biavis
openaire   +2 more sources

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