Results 121 to 130 of about 295 (207)

Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1

open access: yesCytoskeleton, EarlyView.
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen   +2 more
wiley   +1 more source

Experimental study on burning rate and flame geometry in construction tunnel fires under high geothermal conditions

open access: yesDeep Underground Science and Engineering, EarlyView.
Abstract As tunnel construction advances in lengths and depths, the construction of tunnels in high geothermal environments has become increasingly common, raising significant fire risks. In this study, a 1:20 scale model tunnel test platform was constructed to investigate the effects of a high geothermal environment on fire behavior in tunnels during ...
Xiaoxian Fei   +6 more
wiley   +1 more source

Model intercomparison of a cold air pool in the Inn Valley

open access: yes
Cold air pools form in valleys when surrounding terrain prevents horizontal air exchange during calm, stable weather. While these pools can lead to hazardous air pollution and extremely low temperatures, accurately modelling their strongly stable stratification remains a challenge. This study compares four numerical weather prediction models to analyze
openaire   +1 more source

Performance assessment of a potential underground thermal storage facility: Case study of the closed mine Prosper‐Haniel in the Ruhr coal mining area in Germany

open access: yesDeep Underground Science and Engineering, EarlyView.
This study demonstrates the feasibility of an underground closed‐loop thermal storage facility at a post‐mining site, intended for seasonal heat energy storage. Its principal design shows water flow directions in winter and summer (1, 2), heat pumps (3), an upper water reservoir (4), and connecting pipes (5).
Dmytro Rudakov, Oleksandr Inkin
wiley   +1 more source

Topography constrains the climatic response of treeline migration in Taiwan's subalpine forests

open access: yesEcography, EarlyView.
Treelines are moving upslope, but the rates and drivers differ among different regions, globally. Many studies have examined the relationship between treeline movement and climate change, particularly rising temperature, while the role of topographical factors has received much less attention, despite the longstanding recognition of its importance.
Kuan‐Yu Chen   +3 more
wiley   +1 more source

Faster growing and more functionally diverse: global change alters functional trait composition of mountain plant communities in the European Alps

open access: yesEcography, EarlyView.
Understanding how global change reshapes mountain plant communities is essential for predicting biodiversity and ecosystem function in a warming world. Using resurvey data from over 1400 non‐forest vegetation plots across the European Alps, we show that community‐weighted means of key functional traits capturing important dimensions of plant ecological
Sergey Rosbakh   +2 more
wiley   +1 more source

Global threats, local opportunities: ice‐related landforms provide refugia for high‐elevation plants and arthropods

open access: yesEcography, EarlyView.
Ice‐related landforms in mountain areas have been hypothesized to play a key role in the survival of cold‐adapted species threatened by climate change. However, our understanding of such landforms acting as refugia remains speculative. Here we analyse occurrence data, collected through a standardized sampling at 471 sampling points across the European ...
Mauro Gobbi   +4 more
wiley   +1 more source

Ceria Nanostructures Obtained by Hydrothermal Synthesis: Exploring the Experimental Parameter Landscape for Precise Morphology and Size Control

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
Hydrothermal and microwave‐assisted syntheses enable systematic tuning of ceria nanostructure morphology. Chloride counter‐ions direct nanorod growth, while an acetate buffer yields uniform nanocubes whose size (14–26 nm) is tuned via the reactor filling ratio, with microwave heating significantly cutting reaction times to minutes while preserving high
Omar Bettini   +7 more
wiley   +1 more source

Graph Neural Network‐Based Prediction of Building Energy Consumption

open access: yesEnergy Science &Engineering, EarlyView.
A graph neural network that encodes a multi‐zone building as a graph accurately predicts hourly cooling and heating loads across three distinct climates, outperforming Random Forest and XGBoost baselines and serving as a fast surrogate to EnergyPlus simulations for scalable building energy management.
Ali Maboudi Reveshti   +4 more
wiley   +1 more source

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