Results 121 to 130 of about 380,192 (309)

Simulation of tool load for axial forming process with oscillating feed

, 2013
The axial forming process is a method of cold metal forming, which is used for the production of axially symmetric profiles and retractions at full and hollow components.
Lahl, Mike, Popp, Mike, Schuster, Robert, Milbrandt, Matthias, Porstmann, Sebastian, Schiller, Sven, Druwe, Thomas   +6 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Predicting the Ultimate Axial Load Capacity of Joints formed using V-Band Retainers

V-band retainers are widely used in the automotive, aircraft and aerospace industries to connect a pair of circular flanges to provide a joint with good axial strength and torsional rigidity.
Müller, Matthias
core  

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

PRODUCTION OF CASTINGS WITHOUT PINHOLE POROSITY

Литьë и металлургия, 2005
The article is dedicated to pinhole porosity forming in castings at using of the slugs received under Cold-box-amin-process. The mechanism of pinhole porosity forming is revealed, new criteria of its prevention are established, recommendations on its ...
A. N. Boldin, D. A. Soljakov
doaj  

Use of macros in the cold forming tool design process

, 2020
V orodjarstvu strmijo k večji produktivnosti in kvaliteti izdelkov. Konstruiranje orodja je ključna operacija pri celotnem postopku izdelave orodja za hladno preoblikovanje, zato smo v diplomskem delu analizirali uporabo mákrojev v procesu razvoja ...
Knez, Anže
core  

Rolling system design using evolutionary sequential process optimisation [PDF]

, 2008
The design of a rolling system is a multistage process optimization problem involving sequential relationship between consecutive stages. This relationship is peculiar to sequential processes in which the output stock of one stage serves as the input ...
Tiwari, Ashutosh, Roy, Rajkumar, Oduguwa, Victor   +2 more
core  

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source