Results 111 to 120 of about 1,972,874 (316)

Investigation of Flow Parameters for Titanium Cold Spraying using CFD Simulation

, 2010
A comprehensive study of cold gas dynamic spray technology is required for optimising performance and gun design for spraying various materials. Cold spraying technology is a new technique in industry and very limited data is available.
Singh, Tejinder
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal identity and reward contingency signals during rule-reversal

Nature Communications
While animals readily adjust their behavior to adapt to relevant changes in the environment, the neural pathways enabling these changes remain largely unknown.
Diego E. Hernandez, Andrei Ciuparu, Pedro Garcia da Silva, Cristina M. Velasquez, Benjamin Rebouillat, Michael D. Gross, Martin B. Davis, Honggoo Chae, Raul C. Muresan, Dinu F. Albeanu   +9 more
doaj   +1 more source

Cold K Large Ghost in front of Fence

, 2005
Large Cold K ghost against a metal door in South ...
Cummings, Chris, Cold K
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

KLF5 enables dichotomous lineage programs in pancreatic cancer via the AAA+ ATPase coactivators RUVBL1 and RUVBL2

Nature Communications
Lineage plasticity is a hallmark of pancreatic ductal adenocarcinoma (PDAC) and contributes to tumor heterogeneity and therapeutic resistance. Here, we identify KLF5 as a dynamic master regulator of epithelial lineage identity in PDAC, with dichotomous ...
Patrick J. Cunniff, Nicole Sivetz, Damianos Skopelitis, Olaf Klingbeil, Daniel Toobian, Diogo Maia-Silva, Mikala Egeblad, Christopher R. Vakoc   +7 more
doaj   +1 more source

Effects of cold rolling on phase precipitation and phase transformation in a 2507 SDSS [PDF]

, 2011
In the present work 7 samples of UNS S32750 was cold rolled at different rates, analyzed in this state and also after the ageing for 2400s at 400 and 900°C.\nInvestigation was carry out with: OM SEM ( EBSD EDS) Magnetic tests: Forster, Permeameter ...
Bianchi, Marco
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Antibiotic use for common cold

, 2009
Antibiotics do not help patients with an uncomplicated common cold. Antibiotics can have side effects for the individual taking them that range from unpleasant to serious, even lethal.
Timothy W. Kenealy, Bruce Arroll, Arroll, Bruce, Kenealy, Timothy   +3 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source