Results 41 to 50 of about 1,121,070 (292)
Cold-induction of afadin in brown fat supports its thermogenic capacity
Scientific Reports, 2021 The profound energy-expending nature of brown adipose tissue (BAT) thermogenesis makes it an attractive target tissue to combat obesity-associated metabolic disorders.
Morten Lundh +9 more
doaj +1 more source
Cold Atmospheric Plasma for Selectively Ablating Metastatic Breast Cancer Cells
PLoS ONE, 2013 Traditional breast cancer treatments such as surgery and radiotherapy contain many inherent limitations with regards to incomplete and nonselective tumor ablation. Cold atmospheric plasma (CAP) is an ionized gas where the ion temperature is close to room temperature.
Mian Wang +5 more
openaire +4 more sources
Electrophysiological characterisation of neuronal components of cold sensitivity [PDF]
, 2015 Aberrant cold sensitivity is apparent in several neuropathies of peripheral and central origin, and is poorly treated by currently available drugs.
Patel, R
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Historical ablation rates on south-east Greenland glaciers measured in the 1933 warm summer
Polar Research, 2016 Ice ablation rates measured on four glaciers in south-east Greenland in summer 1933 are recovered from an old field book of geologist K. Milthers. These unpublished ablation data are among the first measured in Greenland and were obtained during a warm ...
Bent Hasholt +2 more
doaj +1 more source
Liquid water content in ice estimated through a full-depth ground radar profile and borehole measurements in western Greenland [PDF]
The Cryosphere, 2017 Liquid water content (wetness) within glacier ice is known to strongly control ice viscosity and ice deformation processes. Little is known about wetness of ice on the outer flanks of the Greenland Ice Sheet, where a temperate layer of basal ice exists ...
J. Brown, J. Harper, N. Humphrey
doaj +1 more source
Numerical Modeling of Excimer Laser Curved Surface Ablation [PDF]
, 2013 Laser ablation has been widely used in the fabrication of miniature parts. The technique is also used in the fabrication of micro lens or micro-curved surfaces which find potential applications in various optical, bio- medical, electronics, MEMS ...
Marla, Deepak +3 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Feasibility and accuracy of CARLO© guided extradural anterior clinoidectomy
Current Directions in Biomedical EngineeringAnterior clinoidectomy is a surgical procedure used to access the central skull base, providing access to sellar and parasellar pathologies and vascular lesions in and around the cavernous sinus.
Tu Ha Thanh +5 more
doaj +1 more source
Advanced Science, 2022 The existence of inadequate ablation remains an important cause of treatment failure for loco‐regional ablation therapies. Here, using a preclinical model, it is reported that inadequate microwave ablation (iMWA) induces immunosuppressive niche ...
Shaoyue Li +12 more
doaj +1 more source