Results 101 to 110 of about 29,190 (280)

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó   +4 more
wiley   +1 more source

Development of Multiple Myeloma of the IgA Type in a Patient with Cold Agglutinin Disease: Transformation or Coincidence?

open access: yesCase Reports in Hematology, 2019
Cold agglutinin disease (CAD) is an autoimmune hemolytic anemia and a distinct, clonal bone marrow lymphoproliferative disorder, characterized in most cases by a monoclonal IgMκ serum protein.
Øystein Sefland   +2 more
doaj   +1 more source

Purification and properties of a plant Agglutinin [PDF]

open access: yes, 1958
Thesis (M.A.)--Boston UniversityThis study involved work with extracts of the seeds of Bauhinia purpurea alba, in which an N specific lectin was found by Mäkelä (37) and Boyd and McMaster (16). There were two main purposes in mind.
Everhart, Donald Lee
core   +1 more source

Vaults. III. Vault ribonucleoprotein particles open into flower-like structures with octagonal symmetry. [PDF]

open access: yes, 1991
The structure of rat liver vault ribonucleoprotein particles was examined using several different staining techniques in conjunction with EM and digestion with hydrolytic enzymes.
Chugani, DC   +3 more
core   +2 more sources

Physiological roles of lignins – tuning cell wall hygroscopy and biomechanics

open access: yesNew Phytologist, EarlyView.
Summary Lignins constitute the second most abundant carbon‐storing biopolymers in the biosphere. These phenolic polymers accumulate in different concentrations, compositions, and localisations within and between cell wall layers and cell types. Lignins were acquired during plant terrestrialisation 450 million years ago, and the diversification of their
Edouard Pesquet   +3 more
wiley   +1 more source

Pepducin-mediated cardioprotection via β-arrestin-biased β2-adrenergic receptor-specific signaling [PDF]

open access: yes, 2018
Reperfusion as a therapeutic intervention for acute myocardial infarction-induced cardiac injury itself induces further cardiomyocyte death. β-arrestin (βarr)-biased β-adrenergic receptor (βAR) activation promotes survival signaling responses in vitro ...
Benovic, Jeffrey L.   +7 more
core   +1 more source

Complement C3dg-mediated erythrophagocytosis: Implications for paroxysmal nocturnal hemoglobinuria [PDF]

open access: yes, 2015
The clinical management of paroxysmal nocturnal hemoglobinuria (PNH), a rare but life-threatening hematologic disease, has fundamentally improved with the introduction of a therapeutic that prevents complement-mediated intravascular hemolysis. However, a
Koutsogiannaki, Sophia   +6 more
core   +1 more source

Identification of β‐galactosidases along the secretory pathway of Nicotiana benthamiana that collectively hamper engineering of galactose‐extended glycans on recombinant glycoproteins

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Glycosylation is an important aspect for many biopharmaceuticals, including vaccines against parasitic helminths. Plants, especially Nicotiana benthamiana, have proven to be excellent production hosts for biopharmaceuticals with tailor‐made glycosylation.
Alex van der Kaaij   +7 more
wiley   +1 more source

Vasculitis in an Infant Born to a Mother With Longstanding Cutaneous Polyarteritis Nodosa: A Case Report and Review of Literature

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT We present a neonate born to a mother with a known diagnosis of cutaneous polyarteritis nodosa (cPAN) who presented with acrocyanosis on the first day of life, which progressed to livedo reticularis and eventual digital necrosis and autoamputation.
Marin P. Melloy, Sheilagh Maguiness
wiley   +1 more source

Successful Treatment of Severe Purpura Fulminans With Anakinra

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Purpura fulminans (PF) is a rare, often fatal pediatric condition characterized by intravascular thrombosis and hemorrhagic infarction of the skin. A timely diagnosis and treatment are paramount to prevent the involvement of internal organs, causing disseminated intravascular coagulation and gangrene of the extremities.
Francesco Zulian   +4 more
wiley   +1 more source

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