Results 151 to 160 of about 945,488 (321)

Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids

Advanced Science, Volume 13, Issue 4, 19 January 2026.
To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun, Lifa Zhu, Yutong Li, Jinyan Tang, Tao Zhang, Hengjia Zhang, Wanchu Wang, Lufan Li, Shuhui Bian, Xin Wu   +9 more
wiley   +1 more source

Two Cases of Primary Cold Agglutinin Disease Associated with Megaloblastic Anemia

Case Reports in Hematology, 2015
We report two cases of primary cold agglutinin disease (CAD) associated with megaloblastic anemia in Japanese elderly patients. Case 1 was a 67-year-old male and Case 2 was a 55-year-old male.
Shinsaku Imashuku, Naoko Kudo, Katsushige Takagishi, Katsuyasu Saigo   +3 more
doaj   +1 more source

Phagocytosis of Lymphocytes and Erythrocytes by B‐Cell Lymphoma in a Patient With a Clinical Suspicion of Pure Red Cell Aplasia

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Herein, we report a diagnostically challenging case of a B‐cell lymphoma initially masquerading as pure red cell aplasia (PRCA). The key to diagnosis was the unique finding of phagocytic activity (engulfing erythrocytes and lymphocytes) by atypical mature lymphocytes in both peripheral blood and bone marrow, accompanied by clinical signs of ...
Tuo Cao, Yuting Li, Xiangming Peng
wiley   +1 more source

METTL1‐Mediated N7‐Methylguanosine tRNA Modification Alleviates Cardiac Ischemia/Reperfusion Injury by Modulating Mitochondrial Energy Metabolism

MedComm, Volume 7, Issue 1, January 2026.
During cardiac I/R injury, the level of METTL1 and tRNA m7G modification increases and then leads to CMs’ mitochondrial dysfunction and aggravated cardiac injury by modulating the transcription efficiency of ATPIF1. ABSTRACT Ischemic heart disease is one of the diseases with the highest morbidity and mortality in the world. The N7‐methylguanosine (m7G)
Yue Zhang, Mingyang Leng, Ruonan Wang, Xinyuan Tang, Zhenlu Cai, Liang Wang, Xiaoqi Shao, Hongtao Diao, Qinqiang Long, Xu Li, Yingzi Wu, Yuan Jiang, Haifeng Zhang, Haihai Liang, Jiao Guo   +14 more
wiley   +1 more source

Characterization of a 14 kDa oocyst wall protein of Eimeria tenella and E. acervulina [PDF]

, 2017
We have extracted a protein of 14 kDa from purified oocyst walls of several Eimeria species. Polyclonal antibodies were raised in rats against the 14 kDa proteins of E. acervulina and E. tenella. On immunoblots these antisera reacted in a highly specific
Braun, R., Eggli, P., Eschenbacher, K.-H, Wallach, M.   +3 more
core  

Multiwalled Carbon Nanotubes as Physical Drivers of Chromosome Instability and Inflammatory Responses

Small Structures, Volume 7, Issue 1, January 2026.
This article highlights the fibrous morphology of multiwalled carbon nanotubes as a key factor in their genotoxicity. Fibers physically interfere in cell division, generating binucleated cells and micronuclei, both of which are precursors of carcinogenesis.
Núria Pulido‐Artola, Joan Repullés, Marina Rodriguez‐Muñoz, Teresa Anglada, Anna Genescà   +4 more
wiley   +1 more source

TREATMENT OF COLD AGGLUTININ DISEASE WITH RITUXIMAB

Zdravniški Vestnik, 2008
BACKGROUND Cold agglutinin disease is an uncommon hemolytic anemia associated sometimes withlow-grade B-cell lymphoproliferative disorders. The disease results from increased production of anti erythrocyte antibodies.
Marjana Glaser
doaj  

Cold versus warm autoimmune hemolytic anemia in diffuse large B cell lymphoma: pathogenic and therapeutic implications: a case series

Journal of Medical Case Reports
Background Autoimmune hemolytic anemia-associated diffuse large B cell lymphoma is rare, with distinct pathogenic mechanisms and therapeutic responses in cold agglutinin syndrome (CAS) and warm autoimmune hemolytic anemia subtypes poorly characterized ...
Zhiye Zhang, Xingxing Yu, Jingjing Li, Tianwen Gao   +3 more
doaj   +1 more source

Identification of β‐galactosidases along the secretory pathway of Nicotiana benthamiana that collectively hamper engineering of galactose‐extended glycans on recombinant glycoproteins

Plant Biotechnology Journal, Volume 24, Issue 1, Page 224-238, January 2026.
Summary Glycosylation is an important aspect for many biopharmaceuticals, including vaccines against parasitic helminths. Plants, especially Nicotiana benthamiana, have proven to be excellent production hosts for biopharmaceuticals with tailor‐made glycosylation.
Alex van der Kaaij, Myrna J. M. Bunte, Lisa Nijhof, Sanaz Mokhtari, Hein Overmars, Arjen Schots, Ruud H. P. Wilbers, Pieter Nibbering   +7 more
wiley   +1 more source

Diffusion and physical constraints limit oxidative capacity, capillary supply and size of muscle fibres in mice and humans

Experimental Physiology, Volume 111, Issue 1, Page 212-225, 1 January 2026.
Abstract It has been suggested that angiogenesis during skeletal muscle fibre hypertrophy allows escape from the ‘size constraint’, which is the inverse relationship between oxidative capacity and muscle fibre cross‐sectional area (FCSA). It is, however, not known whether there are any limitations to the combinations of FCSA, oxidative capacity and ...
Hans Degens, Guy A. M. Messa, Jason Tallis, Alessandra Bosutti, Tomas Venckunas, Ismail Adeniran, Rob C. I. Wüst, Paul W. Hendrickse   +7 more
wiley   +1 more source