Clinical Hematology International, 2020 Cold agglutinin disease (CAD) is an uncommon form of cold autoimmune hemolytic anemia (AIHA). It should be considered in the differential diagnosis of elderly patients with unexplained chronic anemia presenting with or without cold-induced symptoms in ...
Amy P. Gabbard, Garrett S. Booth
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Cold Agglutinin Syndrome as the Initial Presentation of Acute Myeloid Leukemia: A Case Report [PDF]
Clinical Case ReportsCold agglutinin‐mediated autoimmune hemolytic anemia, when secondary to viral and bacterial infections or, rarely, malignancy, is called cold agglutinin syndrome.
Mohsen Vakili Sadeghi +2 more
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A middle-aged woman with the initial symptom of acrocyanosis diagnosed with cold agglutinin disease: A case report [PDF]
SAGE Open Medical Case ReportsAutoimmune hemolytic anemia is when autoantibodies attack red blood cells, leading to anemia. Cold agglutinin disease, a subtype of autoimmune hemolytic anemia, accounts for 13%–32% of cases.
Babak Salimi +4 more
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Anesthesia Management of Cold Agglutinin Disease in a Pregnant Patient: A Case Report [PDF]
Clinical Case ReportsCold agglutinin disease (CAD), a rare autoimmune hemolytic anemia (AIHA), is characterized by hemolysis triggered by activation of the classical complement pathway. AIHA is estimated to affect one in 100,000 people in the general population; however, its
Jibran Ikram, Chase Jackson, Sabry Ayad
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Intracapillary Monoclonal IgM Deposition Concomitant With Cold Agglutinin Disease [PDF]
Kidney MedicineMonoclonal gammopathy of renal significance (MGRS) comprises a spectrum of kidney manifestations distinguished by its clinical and pathological presentations.
Silvia M. Titan +4 more
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Sutimlimab for the Treatment of Cold Agglutinin Disease [PDF]
HemaSphere, 2023 Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia and a bone marrow clonal lymphoproliferative disorder. Hemolysis in CAD is complement-dependent and mediated by the classical activation pathway.
Sigbjørn Berentsen
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Navigating cold agglutinin-induced hemolytic anemia in developing countries: A case report and literature review [PDF]
SAGE Open Medical Case ReportsCold agglutinin-induced hemolytic anemia presents diagnostic and management challenges, particularly in resource-limited settings like Pakistan. A 92-year-old male presented with altered consciousness, fever, weakness, and severe asthenia.
Ayesha Amjad +3 more
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Sutimlimab for Cold Agglutinin Disease. [PDF]
J Adv Pract OncolCold agglutinin disease (CAD) is a rare type of autoimmune hemolytic anemia (AIHA) distinct from warm antibody AIHA. One of the ways it is distinct is that CAD is usually not responsive to corticosteroids compared with warm antibody AIHA. Historically, CAD therapy has been limited to immunotherapy or chemoimmunotherapy with varying responses.
Reid M, Fedutes Henderson BA.
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Two Cases of Primary Cold Agglutinin Disease Associated with Megaloblastic Anemia [PDF]
Case Reports in Hematology, 2015 We report two cases of primary cold agglutinin disease (CAD) associated with megaloblastic anemia in Japanese elderly patients. Case 1 was a 67-year-old male and Case 2 was a 55-year-old male.
Shinsaku Imashuku +3 more
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Cold agglutinin disease following SARS‐CoV‐2 and Mycoplasma pneumoniae co‐infections [PDF]
Clinical Case Reports, 2020 SARS‐CoV‐2 and other respiratory co‐infections may occur. As Mycoplasma pneumoniae and various viruses can cause cold agglutinin disease (CAD), the presence of CAD in COVID‐19 patients should indicate the need of investigations for those pathogens.
Chatphatai Moonla +8 more
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