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Organizing Pneumonia in a Case of Cold Agglutinin Disease with Pulmonary Thrombosis. [PDF]
Yabuuchi Y +11 more
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Cold Agglutinin Syndrome and Hemophagocytic Lymphohistiocytosis: An Unusual Combination Caused by Epstein-Barr Virus Infection. [PDF]
Sousa Nunes B +3 more
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Jalink M, Jacobs CF, Khwaja J, et al. Daratumumab monotherapy in refractory warm autoimmune hemolytic anemia and cold agglutinin disease. Blood Adv. 2024;8(11):2622-2634. [PDF]
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Cold Agglutinins and Cold-Agglutinin Disease
Annual Review of Medicine, 1977Since the original descriptions of cold-reactive antibodies at the tum of the century, this group of antibodies and the diseases associated with their appearance have become the focus of a great deal of interest (1-5). Early investigators recognized that a group of these patients had paroxysmal hemoglobinuria on exposure to cold, and a subgroup of ...
John P. Atkinson +2 more
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Vox Sanguinis, 1989
Abstract. An IgMk cold agglutinin reacted with cord blood as well as with adult red blood cells (RBC). The agglutinin reacted strongly with papainized and neuraminidase (RDE)‐treated RBC. It resembled anti‐Me cold agglutinin in these serological findings.
Eiji Kajii, Shigenori Ikemoto
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Abstract. An IgMk cold agglutinin reacted with cord blood as well as with adult red blood cells (RBC). The agglutinin reacted strongly with papainized and neuraminidase (RDE)‐treated RBC. It resembled anti‐Me cold agglutinin in these serological findings.
Eiji Kajii, Shigenori Ikemoto
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Blood, 2013
AbstractCold agglutinin disease is a rare and poorly understood disorder affecting 15% of patients with autoimmune hemolytic anemia. We reviewed the clinical and pathologic features, prognosis, and management in the literature and describe our institutional experience to improve strategies for accurate diagnosis and treatment.
Paul L. Swiecicki +2 more
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AbstractCold agglutinin disease is a rare and poorly understood disorder affecting 15% of patients with autoimmune hemolytic anemia. We reviewed the clinical and pathologic features, prognosis, and management in the literature and describe our institutional experience to improve strategies for accurate diagnosis and treatment.
Paul L. Swiecicki +2 more
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Complement Activation by Cold Agglutinins
Vox Sanguinis, 1992AbstractPurified monoclonal human IgM cold agglutinins (CA) of different specificities (anti‐I, anti‐i, anti‐Pr) were investigated for their complement‐activating capacity in a homologous system. Incubation of human RBC with excess of IgM CA in the cold, and subsequently with human serum at 37°C, resulted in striking differences in hemolysis. Hemolysis
Dieter Roelcke, H. Fritze, M. Kirschfink
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Postgraduate Medicine, 1976
Development of the Coombs test has led to rapid progress in the recognition of various autoimmune hemolytic anemias. Cold agglutinin disease, a relatively rare disorder, occurs in idiopathic and secondary forms, the latter often in association with diseases that alter the immune status.
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Development of the Coombs test has led to rapid progress in the recognition of various autoimmune hemolytic anemias. Cold agglutinin disease, a relatively rare disorder, occurs in idiopathic and secondary forms, the latter often in association with diseases that alter the immune status.
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Variation of Cold Agglutinin Levels
Vox Sanguinis, 1978Abstract. Cold agglutinin levels were determined in 120 individuals ranging in age from 1 to 64 years using untreated and ficin‐treated group O erythrocytes. The geometric mean titer for untreated cells was 5.7±1.1 SEM and for ficin‐treated cells 18.7±1.1 SEM. The mean titers and scores for various blood groups were not significantly different. Titers
Herbert F. Philipsborn +2 more
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Cold Agglutinins and Hypothermia
Archives of Internal Medicine, 1985To the Editor. —An article by Diaz et al1in the August Archives warns about transfusion hemolysis in patients who have cold autoagglutinins and undergo hypothermia during cardiac surgery. The authors suggest a pretransfusion test schema because several cold-mediated complications have now been encountered in such patients.
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