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Molecular characterization of cold agglutinins
Transfusion Science, 2000An unusual bias involving the exclusive usage of the V4-34 gene segment by pathogenic antibodies with I/i antigen specificity has been documented in the literature. In addition, all unmutated and several mutated V4-34 encoded antibodies have been shown to be reactive with the anti-idiotypic monoclonal antibody 9G4.
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Complement, cold agglutinins, and therapy
Blood, 2014In this issue of Blood, Shi and coworkers show that TNT003, a mouse monoclonal antibody targeting complement protein C1s, prevents induction of in vitro hemolysis by cold agglutinins (CA). If successfully transferred into the clinical setting by further studies, these findings may result in a novel therapeutic principle for a frequently difficult ...
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Integrating plant molecular farming and materials research for next-generation vaccines
Nature Reviews Materials, 2021Young Hun Chung +2 more
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