Results 261 to 270 of about 945,488 (321)
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Complement‐mediated hemolysis persists year round in patients with cold agglutinin disease
Transfusion, 2021Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia mediated by immunoglobulin M autoantibodies that bind to the “I” antigen on erythrocytes.
A. Röth +7 more
semanticscholar +1 more source
American journal of hematology/oncology, 2021
Primary cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia mediated by monoclonal IgM autoantibodies that bind to the blood group I antigen resulting in erythrocyte agglutination and complement activation. Primary cold agglutinin disease
A. Małecka +8 more
semanticscholar +1 more source
Primary cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia mediated by monoclonal IgM autoantibodies that bind to the blood group I antigen resulting in erythrocyte agglutination and complement activation. Primary cold agglutinin disease
A. Małecka +8 more
semanticscholar +1 more source
Blood, 2013
AbstractCold agglutinin disease is a rare and poorly understood disorder affecting 15% of patients with autoimmune hemolytic anemia. We reviewed the clinical and pathologic features, prognosis, and management in the literature and describe our institutional experience to improve strategies for accurate diagnosis and treatment.
Paul L, Swiecicki +2 more
openaire +2 more sources
AbstractCold agglutinin disease is a rare and poorly understood disorder affecting 15% of patients with autoimmune hemolytic anemia. We reviewed the clinical and pathologic features, prognosis, and management in the literature and describe our institutional experience to improve strategies for accurate diagnosis and treatment.
Paul L, Swiecicki +2 more
openaire +2 more sources
Transfusion, 2021
Primary cold agglutinin disease (CAD) is a monoclonal antibody (M‐protein) and complement‐mediated chronic hemolytic disease process. Antibody glycosylation can play a role in both antibody half‐life and complement fixation.
J. Juskewitch +6 more
semanticscholar +1 more source
Primary cold agglutinin disease (CAD) is a monoclonal antibody (M‐protein) and complement‐mediated chronic hemolytic disease process. Antibody glycosylation can play a role in both antibody half‐life and complement fixation.
J. Juskewitch +6 more
semanticscholar +1 more source
Postgraduate Medicine, 1976
Development of the Coombs test has led to rapid progress in the recognition of various autoimmune hemolytic anemias. Cold agglutinin disease, a relatively rare disorder, occurs in idiopathic and secondary forms, the latter often in association with diseases that alter the immune status.
openaire +2 more sources
Development of the Coombs test has led to rapid progress in the recognition of various autoimmune hemolytic anemias. Cold agglutinin disease, a relatively rare disorder, occurs in idiopathic and secondary forms, the latter often in association with diseases that alter the immune status.
openaire +2 more sources
Rare side effect caused by atezolizumab, an immune checkpoint inhibitor: Cold agglutinin disease
Journal of Oncology Pharmacy Practice, 2021Introduction Immune checkpoint inhibitors are drugs that are included in the guidelines of hematological and solid cancer treatments, give highly effective results and increase T cell functionality.
O. Acikgoz +3 more
semanticscholar +1 more source
Anaesthesia, 1980
Summary An unusual case of re‐exploration of the site of previous ventricular aneurysmectomy is reported. The conduct of cardiopulmonary bypass was complicated by the presence of cold agglutinins with a wide thermal range active up to 30°C.
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Summary An unusual case of re‐exploration of the site of previous ventricular aneurysmectomy is reported. The conduct of cardiopulmonary bypass was complicated by the presence of cold agglutinins with a wide thermal range active up to 30°C.
openaire +2 more sources
Vox Sanguinis, 1989
Abstract. An IgMk cold agglutinin reacted with cord blood as well as with adult red blood cells (RBC). The agglutinin reacted strongly with papainized and neuraminidase (RDE)‐treated RBC. It resembled anti‐Me cold agglutinin in these serological findings.
E, Kajii, S, Ikemoto
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Abstract. An IgMk cold agglutinin reacted with cord blood as well as with adult red blood cells (RBC). The agglutinin reacted strongly with papainized and neuraminidase (RDE)‐treated RBC. It resembled anti‐Me cold agglutinin in these serological findings.
E, Kajii, S, Ikemoto
openaire +2 more sources
Blood, 2010
In this issue of Blood, Berentsen and coworkers describe a high response rate which is durable in some patients who receive combination fludarabine and rituximab for chronic cold agglutinin disease (CAD). If confirmed, this is a significant advance in therapy for a frequently difficult clinical problem.
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In this issue of Blood, Berentsen and coworkers describe a high response rate which is durable in some patients who receive combination fludarabine and rituximab for chronic cold agglutinin disease (CAD). If confirmed, this is a significant advance in therapy for a frequently difficult clinical problem.
openaire +2 more sources
Cold Agglutinins and Hypothermia
Archives of Internal Medicine, 1985To the Editor. —An article by Diaz et al1in the August Archives warns about transfusion hemolysis in patients who have cold autoagglutinins and undergo hypothermia during cardiac surgery. The authors suggest a pretransfusion test schema because several cold-mediated complications have now been encountered in such patients.
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