Results 31 to 40 of about 945,488 (321)
Hematology, 2023 Background: Cold agglutinin disease (CAD) is immune-mediated hemolytic anemia. The disease is caused by cold reactive autoantibodies that induce hemolysis through the activation of the complement pathway.
Abdelaziz Mohamed +3 more
semanticscholar +1 more source
Journal of Cardiothoracic Surgery, 2023 Background Cold agglutinin disease can lead to significant complications, especially for patients undergoing arch repair requiring hypothermic circulatory arrest. Rituximab and plasmapheresis are treatments for cold agglutinin disease.
Atsuyuki Mitsuishi +5 more
doaj +1 more source
Current Medicine Research and Practice, 2022 Cold agglutinin disease, commonly affecting females in the their seventh decade of life, is otherwise a rare entity and has an incidence of one case per million people per year.
Vivek Ranjan +4 more
doaj +1 more source
Sutimlimab for treatment of cold agglutinin disease: why, how and for whom?
Immunotherapy, 2022 Therapies for cold agglutinin disease have been directed at the pathogenic B-cell clone. Sutimlimab, a monoclonal antibody that targets C1s, is the first complement inhibitor to be extensively studied in cold agglutinin disease.
S. Berentsen +3 more
semanticscholar +1 more source
Cold agglutinin syndrome in a patient with human immunodeficiency virus infection
Journal of Clinical and Scientific Research, 2023 A 44-year-old female with no prior comorbidities presented with a history of easy fatiguability and yellowish discolouration of eyes of 3 months duration. On examination, she had pallor and icterus. Jugular venous pressure was elevated.
Abhilash Naini +4 more
doaj +1 more source
A novel method for negating cold agglutination interference by dithiothreitol during complete blood count and peripheral blood smear: a case study [PDF]
The Ukrainian Biochemical Journal, 2017 Cold agglutinin disease is an autoimmune disorder that is characterized by antibodies attacking polysaccharide antigens on one’s own erythrocytes.
Hamit Yasar Ellidag +2 more
doaj +1 more source
JMIR Formative Research, 2022 Background Cold agglutinin disease (CAD) is a rare disorder, affecting 15% of patients with autoimmune hemolytic anemia. Few studies have assessed CAD symptoms and their impact on daily life, but these studies did not address the patients’ perspectives ...
Florence Joly +4 more
semanticscholar +1 more source
Use of Rituximab in autoimmune hemolytic anemia associated with non-hodgkin lymphomas [PDF]
, 2011 The association between non-Hodgkin lymphomas and autoimmune disorders is a well-known event. Also autoimmune hemolytic anemia (AHA), although much more frequent in patients with chronic lymphocytic leukemia (CLL), has been described in this group of ...
Fozza, Claudio +1 more
core +4 more sources
Frontiers in Immunology, 2021 Daratumumab is a monoclonal antibody directed against the transmembrane glycoprotein CD38 expressed on plasma cells and lymphoplasmocytes, with a proven efficacy in multiple myeloma.
A. Zaninoni +7 more
semanticscholar +1 more source
A novel method for demonstrating cold agglutinin disease: a case report
Journal of Medical Case Reports, 2018 Background Cold agglutinin disease is a rare disorder characterized by an autoimmune hemolytic anemia occurring at low temperatures. Physical examination findings, often limited to acrocyanosis, are combined with a thermal amplitude test to help ...
Thomas A. Vo +3 more
doaj +1 more source