Results 41 to 50 of about 29,190 (280)

Cold Agglutinin Disease: Improved Understanding of Pathogenesis Helps Define Targets for Therapy

Hemato, 2022
The last 2 decades have seen great progress in understanding the pathogenesis of cold agglutinin disease (CAD) and development of effective therapies.
Sigbjørn Berentsen, Shirley D’Sa, Ulla Randen, Agnieszka Małecka, Josephine M. I. Vos   +4 more
doaj   +1 more source

Protein glycosylation as a diagnostic and prognostic marker of chronic inflammatory gastrointestinal and liver diseases [PDF]

, 2020
Glycans are sequences of carbohydrates that are added to proteins or lipids to modulate their structure and function. Glycans modify proteins required for regulation of immune cells, and alterations have been associated with inflammatory conditions.
Callewaert, Nico, Colombel, Jean-Frederic, Dias, Ana M, Pinho, Salome S, Van Vlierberghe, Hans, Verhelst, Xavier, Vermeire, Severine   +6 more
core   +1 more source

Clinical characteristics and outcome of patients with autoimmune hemolytic anemia (AIHA) uniformly defined as primary by a diagnostic work-up [PDF]

, 2016
Primary autoimmune hemolytic anemia (P-AIHA) is a relatively uncommon and hetereogeneous disease characterized by the destruction of red blood cells due to anti-erythrocyte autoantibodies (AeAbs) in the absence of an associated disease [1–3].
ARMIENTO, DANIELE, CARONNA, Roberto, COLAFIGLI, GIOIA, Coluzzi, S, De Propris, Ms, FERRETTI, ANTONIETTA, FOA, Roberto, GIOVANNETTI, GIANLUCA, GIRELLI, Gabriella, GUARINI, Anna, LA ROCCA, URSULA, MAURO, Francesca Romana, MOLICA, MATTEO, Morano, G, Paoloni, F, Trastulli, F   +15 more
core   +1 more source

Glucocorticoid-Responsive Cold Agglutinin Disease in a Patient with Rheumatoid Arthritis

Case Reports in Rheumatology, 2015
A 57-year-old man with rheumatoid arthritis developed severe anemia during treatment with adalimumab plus methotrexate. Cold agglutinin disease was diagnosed because haptoglobin was undetectable, cold agglutinin was positive (1 : 2048), and the direct ...
Kyoko Honne, Takao Nagashima, Masahiro Iwamoto, Toyomi Kamesaki, Seiji Minota   +4 more
doaj   +1 more source

The role of CDC48 in the retro-translocation of non-ubiquitinated toxin substrates in plant cells [PDF]

, 2009
When the catalytic A subunits of the castor bean toxins ricin and Ricinus communis agglutinin (denoted as RTA and RCA A, respectively) are delivered into the endoplasmic reticulum (ER) of tobacco protoplasts, they become substrates for ER ...
Aldo Ceriotti, Allen, Bays, Brandizzi, Braun, Caldwell, Campbell, Carlson, Carter, Carvalho, Chaddock, Christopher J. Snowden, Contento, Dalal, Day, Deak, Deeks, Denecke, Denic, Di Cola, Di Cola, Feiler, Frigerio, Hellens, Hunter, J. Michael Lord, Jarosch, Jolliffe, Kirst, Klein, Kothe, Lee, Lord, Lorenzo Frigerio, Lynne M. Roberts, Maliga, Martinez, Meusser, Muller, Nicholas A. Jolliffe, Pedrazzini, Pimpl, Rabinovich, Rancour, Rape, Richard S. Marshall, Richly, Roberts, Roberts, Roberts, Romisch, Schmid, Schuberth, Simpson, Smalle, Swanson, Tabe, Tsai, Vashist, Vashist, Vitale, Wahlman, Wiertz, Wojcik, Wojcik, Worthington, Ye, Ye, Yoshida, Yoshida   +69 more
core   +2 more sources

Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report

Thrombosis Journal, 2012
A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection. Although acrocyanosis is
Karunarathne Suneth, Weerasinghe Sajitha, Govindapala Dumitha, Fernando Harshini, Jayaratne Bhaddika   +4 more
doaj   +1 more source

Obinutuzumab for the Treatment of Cold Agglutinin Disease: A Case Report [PDF]

Turkish Journal of Hematology
Siyuan Li, Kaini Shen, Lu Zhang
doaj   +2 more sources

Activation of Complement by Cold Agglutinins [PDF]

Transfusion Medicine and Hemotherapy, 1994
<i>Objective:</i> To review recent reports on the interaction of cold agglutinins with the complement system and its relevance to cold agglutinin disease. <i>Data Sources:</i> Review articles and original papers have been selected for this contribution.
K. Knoblauch, M. Kirschfink, D. Roelcke
openaire   +2 more sources

Cold agglutinin disease [PDF]

Hematology, 2016
AbstractPrimary chronic cold agglutinin disease (CAD) is a well-defined clinicopathologic entity in which a specific, clonal lymphoproliferative B-cell bone marrow disorder results in autoimmune hemolytic anemia. The immune hemolysis is entirely complement-dependent, predominantly mediated by activation of the classical pathway and phagocytosis of ...
openaire   +3 more sources

COVID-19 and Cold Agglutinin Hemolytic Anemia

TH Open, 2020
Novel coronavirus disease 2019 (COVID-19) has spread throughout the world and has infected close to 4 million people. It commonly presents with fever, cough, and fatigue. Due to the high inflammatory response, it is suggested that the coagulation cascade
Diana V. Maslov, Victoria Simenson, Suma Jain, Ambuga Badari   +3 more
doaj   +1 more source